Ripk1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ripk1
receptor (TNFRSF)-interacting serine-threonine kinase 1
MGI:108212

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ripk1^tm1.1Vmd/Ripk1^tm1.1Vmd involves: C57BL/6N	abnormal brown adipose tissue physiology	J:209137
	abnormal colon morphology	J:209137
	abnormal intestine morphology	J:209137
	increased cell death	J:209137
	increased thymocyte apoptosis	J:209137
	neonatal lethality	J:209137
Ripk1^tm1Geno/Ripk1^tm1Geno involves: C57BL/6	abnormal body temperature	J:209137
	decreased sensitivity to induced cell death	J:209137
	normal mortality/aging	J:209137
Ripk1^tm1Led/Ripk1^tm1Led involves: 129S6/SvEvTac	abnormal brown adipose tissue morphology	J:46522
	abnormal dermal layer morphology	J:46522
	abnormal immune system organ morphology	J:46522
	abnormal leukocyte cell number	J:46522
	abnormal lymph node morphology	J:46522
	abnormal thymus morphology	J:46522
	decreased body weight	J:46522
	decreased thymocyte number	J:46522
	edema	J:46522
	increased spleen red pulp amount	J:46522
	lymph node inflammation	J:46522
	lymph node necrosis	J:46522
	postnatal lethality, complete penetrance	J:46522

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24