Ripk1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ripk1
receptor (TNFRSF)-interacting serine-threonine kinase 1
MGI:108212

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ripk1^tm1.1Vmd/Ripk1^tm1.1Vmd involves: C57BL/6N	abnormal brown adipose tissue physiology	J:209137
	abnormal colon morphology	J:209137
	abnormal intestine morphology	J:209137
	increased cell death	J:209137
	increased thymocyte apoptosis	J:209137
	neonatal lethality	J:209137
Ripk1^tm1Geno/Ripk1^tm1Geno involves: C57BL/6	abnormal body temperature	J:209137
	decreased sensitivity to induced cell death	J:209137
	normal mortality/aging	J:209137
Ripk1^tm1Led/Ripk1^tm1Led involves: 129S6/SvEvTac	abnormal brown adipose tissue morphology	J:46522
	abnormal dermal layer morphology	J:46522
	abnormal immune system organ morphology	J:46522
	abnormal leukocyte cell number	J:46522
	abnormal lymph node morphology	J:46522
	abnormal thymus morphology	J:46522
	decreased body weight	J:46522
	decreased thymocyte number	J:46522
	edema	J:46522
	increased spleen red pulp amount	J:46522
	lymph node inflammation	J:46522
	lymph node necrosis	J:46522
	postnatal lethality, complete penetrance	J:46522

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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