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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Alx4
aristaless-like homeobox 4
MGI:108359
30 phenotypes from 6 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Alx4Lst-2J/Alx4+
C57BL/6J-Alx4Lst-2J/J 		preaxial polydactyly J:223288
short snout J:223288
Alx4Lst-2J/Alx4Lst-2J
C57BL/6J-Alx4Lst-2J/J 		abnormal frontal bone morphology J:223288
abnormal neurocranium morphology J:223288
alopecia J:223288
cataract J:223288
eyelids open at birth J:223288
ocular hypertelorism J:223288
perinatal lethality, incomplete penetrance J:223288
polydactyly J:223288
short snout J:223288
Alx4Lst-2J/Alx4Lst-2J
involves: C57BL/6J * CD-1 		normal craniofacial phenotype J:320497
failure of eyelid fusion J:320497
Alx4Lst-2J/Alx4lst-J
involves: C3H/FeJLe * C57BL/6J 		eyelids open at birth J:223288
polydactyly J:223288
Alx4lst-Alb/Alx4+
involves: C3H/HeJ * C57BL/6 		abnormal limb morphology J:49152
preaxial polydactyly J:49152
Alx4lst-Alb/Alx4lst-Alb
involves: C3H/HeJ * C57BL/6 		prenatal lethality, complete penetrance J:49152
Alx4lst-J/Alx4lst-J
B6C3Fe a/a-Alx4lst-J/J 		small pubis J:101708
Alx4m1Btlr/Alx4m1Btlr
C57BL/6J-Alx4m1Btlr 		delayed hair appearance J:132742
focal dorsal hair loss J:132742
preaxial polydactyly J:132742
short snout J:132742
upturned snout J:132742
Alx4M1Yzcm/Alx4+
C57BL/6-Alx4M1Yzcm 		preaxial polydactyly J:199512
Alx4M1Yzcm/Alx4M1Yzcm
C57BL/6-Alx4M1Yzcm 		abnormal abdominal wall morphology J:199512
abnormal muscle morphology J:199512
absent pubis J:199512
alopecia J:199512
eyelids open at birth J:199512
herniated abdominal wall J:199512
neonatal lethality, incomplete penetrance J:199512
omphalocele J:199512
preaxial polydactyly J:199512
short tibia J:199512
small parietal bone J:199512
thin skin J:199512
Alx4tm1Rwi/Alx4+
involves: 129S6/SvEvTac 		no abnormal phenotype detected J:43769
Alx4tm1Rwi/Alx4+
involves: 129S6/SvEvTac * C57BL/6J 		polydactyly J:49152
Alx4tm1Rwi/Alx4tm1Rwi
involves: 129S6/SvEvTac 		abnormal parietal bone morphology J:43769
abnormal zone of polarizing activity morphology J:43769
herniated abdominal wall J:43769
perinatal lethality, incomplete penetrance J:43769
polydactyly J:43769
Alx4tm1Rwi/Alx4tm1Rwi
involves: 129S6/SvEvTac * C57BL/6J 		abnormal parietal bone morphology J:43769
herniated abdominal wall J:43769
perinatal lethality, incomplete penetrance J:43769
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory