Npy2r Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Npy2r
neuropeptide Y receptor Y2
MGI:108418

57 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Npy2r^em1(IMPC)H/Npy2r^em1(IMPC)H C57BL/6N-Npy2r^em1(IMPC)H/H	abnormal locomotor behavior	J:211773
	enlarged spleen	J:211773
	increased spleen weight	J:211773
	prolonged QRS complex duration	J:211773
Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz involves: 129X1/SvJ	abnormal food intake	J:129742
Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz involves: 129X1/SvJ * BALB/cJ * C57BL/6	abnormal eating behavior	J:84570
	abnormal trabecular bone morphology	J:84570
	decreased body weight	J:84570
	decreased osteoclast cell number	J:84570
	decreased white adipose tissue amount	J:84570
	increased circulating pancreatic peptide level	J:84570
	increased trabecular bone thickness	J:84570
Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz involves: 129X1/SvJ * C57BL/6	abnormal eating behavior	J:77345
	abnormal olfactory sensory neuron morphology	J:132859
	abnormal postnatal subventricular zone morphology	J:132859
	abnormal rostral migratory stream morphology	J:132859
	abnormal spatial learning	J:121312
	abnormal testosterone level	J:129609
	abnormal trabecular bone morphology	J:97455
	decreased anxiety-related response	J:96222
	decreased body weight	J:77345
	decreased circulating corticosterone level	J:107169
	decreased circulating insulin level	J:77345
	decreased neuronal precursor cell number	J:132859
	decreased white adipose tissue amount	J:77345
	impaired long-term object recognition memory	J:121312
	increased circulating insulin-like growth factor I level	J:129609
	increased circulating pancreatic peptide level	J:77345
	increased fluid intake	J:115774
	increased growth hormone level	J:129609
	increased susceptibility to pharmacologically induced seizures	J:124729
	increased susceptibility to xenobiotic induced morbidity/mortality	J:124729
	increased trabecular bone thickness	J:97455
Npy2r^tm1Hhz/Npy2r^tm1Hhz involves: 129X1/SvJ * C57BL/6	abnormal circulating hormone level	J:77345
	abnormal circulating insulin level	J:77345
	abnormal food intake	J:77345
	abnormal trabecular bone morphology	J:97455
	normal adipose tissue phenotype	J:77345
	decreased body weight	J:77345
	decreased osteoclast cell number	J:97455
	normal homeostasis/metabolism phenotype	J:77345
	increased bone mineralization	J:97455
	increased bone ossification	J:97455
	increased circulating corticosterone level	J:77345, J:97455
	increased circulating pancreatic peptide level	J:77345
	increased trabecular bone thickness	J:97455
Npy2r^tm1Pern/Npy2r^tm1Pern involves: 129	abnormal righting response	J:71826
Npy2r^tm1Pern/Npy2r^tm1Pern involves: 129	abnormal sleep duration	J:71826
Npy2r^tm1Pern/Npy2r^tm1Pern involves: 129/Sv * BALB/c	abnormal circadian regulation of heart rate	J:57961
	decreased energy expenditure	J:57961
	decreased locomotor activity	J:57961
	decreased response to leptin	J:57961
	increased body weight	J:57961
	increased total fat pad weight	J:57961
	polyphagia	J:57961
Npy2r^tm1Pern/Npy2r^tm1Pern involves: 129/Sv * BALB/cJ	alcohol aversion	J:102430
Npy2r^tm1Pern/Npy2r^tm1Pern involves: 129/Sv * BALB/cJ	increased fluid intake	J:102430
Npy^{tm1(rtTA,tetO-cre/EGFP)Snby}/Npy⁺ Npy2r^tm1Hhz/Npy2r^tm1Hhz involves: 129X1/SvJ * C57BL/6	abnormal glucose homeostasis	J:162000
	abnormal locomotor activation	J:162000
	normal behavior/neurological phenotype	J:162000
	decreased body temperature	J:162000
	decreased white adipose tissue mass	J:162000
	normal growth/size/body region phenotype	J:162000
	increased body fat mass	J:162000
	increased liver triglyceride level	J:162000
	increased oxygen consumption	J:162000
	increased susceptibility to weight gain	J:162000
	increased trabecular bone volume	J:162000
	increased white adipose tissue mass	J:162000
	normal renal/urinary system phenotype	J:162000

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