Npy2r Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Npy2r
neuropeptide Y receptor Y2
MGI:108418

43 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Lep^ob/Lep^ob Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz involves: 129X1/SvJ * C57BL/6	abnormal adipose tissue amount	J:107169
	abnormal circulating glucose level	J:107169
	abnormal circulating insulin level	J:107169
	abnormal intestine morphology	J:107169
	decreased circulating corticosterone level	J:107169
	decreased circulating testosterone level	J:107169
	decreased epididymal fat pad weight	J:107169
	decreased lean body mass	J:107169
	decreased mesenteric fat pad weight	J:107169
	decreased testis weight	J:107169
	female infertility	J:76479
	increased body weight	J:107169
	increased circulating cholesterol level	J:107169
	increased circulating triglyceride level	J:107169
	increased kidney weight	J:107169
	increased liver weight	J:107169
	increased pancreas weight	J:107169
	male infertility	J:76479, J:107169
	polyphagia	J:107169
Lep^ob/Lep^ob Npy2r^tm1Pern/Npy2r^tm1Pern involves: 129 * BALB/c * C57BL/10J	decreased body weight	J:102651
	decreased circulating free fatty acids level	J:102651
	decreased circulating glucose level	J:102651
	decreased circulating LDL cholesterol level	J:102651
	increased circulating cholesterol level	J:102651
	increased circulating HDL cholesterol level	J:102651
	increased triglyceride level	J:102651
Npy1r^tm1Pern/Npy1r^tm1Pern Npy2r^tm1Pern/Npy2r^tm1Pern involves: 129	abnormal righting response	J:71826
Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz Npy4r^tm1.1Hhz/Npy4r^tm1.1Hhz involves: 129X1/SvJ * BALB/cJ * C57BL/6	abnormal bone mineralization	J:84570
	abnormal bone ossification	J:84570
	abnormal bone structure	J:84570
	abnormal eating behavior	J:84570
	abnormal osteoblast physiology	J:84570
	abnormal trabecular bone morphology	J:84570
	decreased body weight	J:84570
	decreased brown adipose tissue amount	J:84570
	decreased circulating insulin level	J:84570
	decreased circulating leptin level	J:84570
	decreased compact bone thickness	J:84570
	decreased white adipose tissue amount	J:84570
	increased circulating pancreatic peptide level	J:84570
	increased trabecular bone thickness	J:84570
Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz Npy4r^tm1.1Hhz/Npy4r^tm1.1Hhz involves: 129X1/SvJ * C57BL/6	abnormal testosterone level	J:129609
	increased circulating insulin-like growth factor I level	J:129609
	increased growth hormone level	J:129609
Npy2r^tm1Pern/Npy2r^tm1Pern Npy5r^tm1Pern/Npy5r^tm1Pern involves: 129/Sv * BALB/c	normal behavior/neurological phenotype	J:71826

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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