Kif1b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kif1b
kinesin family member 1B
MGI:108426

32 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kif1b^Gt(XC445)Byg/Kif1b^Gt(XC445)Byg B6.129P2-Kif1b^Gt(XC445)Byg	embryonic lethality	J:94077
Kif1b^{tm1b(KOMP)Wtsi}/Kif1b⁺ C57BL/6N-Kif1b^{tm1b(KOMP)Wtsi}/J	decreased blood urea nitrogen level	J:211773
	decreased exploration in new environment	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
	increased circulating chloride level	J:211773
	increased circulating sodium level	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
	increased startle reflex	J:211773
	increased vertical activity	J:211773
Kif1b^{tm1b(KOMP)Wtsi}/Kif1b^{tm1b(KOMP)Wtsi} C57BL/6N-Kif1b^{tm1b(KOMP)Wtsi}/J	abnormal embryo size	J:211773
	abnormal facial morphology	J:211773
	abnormal head shape	J:211773
	abnormal limb morphology	J:211773
	abnormal outer ear morphology	J:211773
	hemorrhage	J:211773
	preweaning lethality, complete penetrance	J:211773
	unresponsive to tactile stimuli	J:211773
Kif1b^tm1Noh/Kif1b⁺ involves: 129S4/SvJae * C57BL/6J	abnormal axonal transport	J:69772
	abnormal motor coordination/balance	J:69772
	impaired coordination	J:69772
	progressive muscle weakness	J:69772
Kif1b^tm1Noh/Kif1b^tm1Noh involves: 129S4/SvJae * C57BL/6J	abnormal brain commissure morphology	J:69772
	abnormal brainstem morphology	J:69772
	abnormal hippocampus morphology	J:69772
	abnormal spinal cord ventral horn morphology	J:69772
	abnormal synaptic vesicle number	J:69772
	decreased brain size	J:69772
	decreased neuron number	J:69772
	lordosis	J:69772
	neonatal lethality, complete penetrance	J:69772
	respiratory failure	J:69772
	unresponsive to tactile stimuli	J:69772

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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