Lpar1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lpar1
lysophosphatidic acid receptor 1
MGI:108429

31 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lpar1^mpc125H/Lpar1^mpc125H involves: BALB/c * C3H/HeH * C57BL/6J	decreased body fat mass	J:234901
	decreased body weight	J:234901
	decreased bone mineral density	J:234901
Lpar1^{tm1b(EUCOMM)Wtsi}/Lpar1⁺ C57BL/6N-Lpar1^{tm1b(EUCOMM)Wtsi}/J	cataract	J:211773
	improved glucose tolerance	J:211773
	increased fasting circulating glucose level	J:211773
Lpar1^{tm1b(EUCOMM)Wtsi}/Lpar1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Lpar1^{tm1b(EUCOMM)Wtsi}/J	preweaning lethality, complete penetrance	J:211773
Lpar1^tm1Jch/Lpar1^tm1Jch involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal Schwann cell morphology	J:65882
	abnormal sciatic nerve morphology	J:65882
	abnormal suckling behavior	J:65882
	decreased body size	J:65882
	decreased Schwann cell number	J:65882
	decreased total body fat amount	J:65882
	exencephaly	J:65882
	hemorrhage	J:65882
	neonatal lethality, incomplete penetrance	J:65882
	ocular hypertelorism	J:65882
	postnatal growth retardation	J:65882
	postnatal lethality, incomplete penetrance	J:65882
	short snout	J:65882
Lpar1^tm1Mcox/Lpar1^tm1Mcox B6.129P2-Lpar1^tm1Mcox	abnormal amino acid level	J:87198
	abnormal craniofacial morphology	J:87198
	abnormal serotonin level	J:87198
	decreased body height	J:87198
	decreased body mass index	J:87198
	decreased locomotor activity	J:87198
	decreased prepulse inhibition	J:87198
	increased dopamine level	J:87198
	long incisors	J:87198
	normal nervous system phenotype	J:87198
	ocular hypertelorism	J:87198
	perinatal lethality, incomplete penetrance	J:87198
	postnatal lethality, incomplete penetrance	J:87198
	short snout	J:87198

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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