Fzd3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fzd3
frizzled class receptor 3
MGI:108476

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fzd3^tm1(FZD3)Lex/Fzd3^tm1(FZD3)Lex involves: 129S5/SvEvBrd * C57BL/6J	normal cellular phenotype	J:185566
	decreased depression-related behavior	J:185566
	decreased prepulse inhibition	J:185566
	dilated lateral ventricle	J:185566
	dilated third ventricle	J:185566
	normal growth/size/body region phenotype	J:185566
	impaired cued conditioning behavior	J:185566
	reduced sensorimotor gating	J:185566
Fzd3^tm1Nat/Fzd3⁺ Fzd6^tm1Nat/Fzd6^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	oligozoospermia	J:105752
	reduced male fertility	J:105752
Fzd3^tm1Nat/Fzd3^tm1Nat Fzd6^tm1Nat/Fzd6^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cochlea morphology	J:105752
	abnormal cochlear outer hair cell morphology	J:105752
	abnormal crista ampullaris morphology	J:105752
	abnormal orientation of inner hair cell stereociliary bundles	J:105752
	abnormal tectorial membrane morphology	J:105752
	curly tail	J:105752
	eyelids open at birth	J:105752
	normal hearing/vestibular/ear phenotype	J:105752
	neonatal lethality, complete penetrance	J:105752
	open neural tube	J:105752

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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