Oxtr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Oxtr
oxytocin receptor
MGI:109147

23 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Oxtr^{tm1.1(KOMP)Vlcg}/Oxtr^{tm1.1(KOMP)Vlcg} C57BL/6N-Oxtr^{tm1.1(KOMP)Vlcg}/Rbrc	increased circulating LDL cholesterol level	J:211773
Oxtr^tm1.1Knis/Oxtr^tm1.1Knis involves: 129P2/OlaHsd * C57BL/6J	abnormal maternal nurturing	J:102924
	abnormal pup retrieval	J:102924
	abnormal social investigation	J:102924
	absent maternal crouching	J:102924
	decreased vocalization	J:102924
	increased aggression towards mice	J:102924
	increased locomotor activity	J:102924
	lactation failure	J:102924
Oxtr^tm1.1Wsy/Oxtr^tm1.1Wsy involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	no abnormal phenotype detected	J:137445
Oxtr^tm1.1Wsy/Oxtr^tm1.1Wsy Tg(Camk2a-cre)1Szi/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL	abnormal social investigation	J:137445
	decreased body weight	J:137445
	normal endocrine/exocrine gland phenotype	J:137445
Oxtr^tm1.2Wsy/Oxtr⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL	decreased litter size	J:137445
Oxtr^tm1.2Wsy/Oxtr^tm1.2Wsy involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL	abnormal milk ejection	J:137445
	abnormal social investigation	J:137445
	normal behavior/neurological phenotype	J:137445
	normal growth/size/body region phenotype	J:137445
	normal integument phenotype	J:137445
	normal muscle phenotype	J:137445
	normal reproductive system phenotype	J:137445
Oxtr^tm1Knis/Oxtr^tm1Knis B6N.129P2-Oxtr^tm1Knis	abnormal contextual conditioning behavior	J:203893
	abnormal learning/memory/conditioning	J:203893
	abnormal social investigation	J:203893
	normal behavior/neurological phenotype	J:203893
Oxtr^tm1Wsy/Oxtr^tm1Wsy involves: 129S1/Sv * 129X1/SvJ	abnormal brain morphology	J:137445
Oxtr^tm1Wsy/Oxtr^tm1Wsy involves: 129S1/Sv * 129X1/SvJ	normal nervous system phenotype	J:137445

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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