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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ltbp1
latent transforming growth factor beta binding protein 1
MGI:109151
50 phenotypes from 6 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ltbp1b2b1000Clo/Ltbp1b2b1000Clo
C57BL/6J-Ltbp1b2b1000Clo 		dilated renal tubule J:175213
double outlet right ventricle J:175213
interrupted aortic arch J:175213
persistent truncus arteriosus J:175213
polycystic kidney J:175213
renal glomerulus cyst J:175213
right aortic arch J:175213
vascular ring J:175213
Ltbp1tm1a(EUCOMM)Wtsi/Ltbp1+
B6JTyr;B6N-Ltbp1tm1a(EUCOMM)Wtsi/Wtsi 		increased leukocyte cell number J:175295
Ltbp1tm1a(EUCOMM)Wtsi/Ltbp1tm1a(EUCOMM)Wtsi
B6JTyr;B6N-Ltbp1tm1a(EUCOMM)Wtsi/Wtsi 		abnormal cranium morphology J:175295
abnormal incisor morphology J:175295
abnormal radius morphology J:175295
abnormal snout morphology J:175295
abnormal tooth morphology J:175295
abnormal ulna morphology J:175295
decreased body length J:175295
decreased body weight J:175295
decreased bone mineral content J:175295
decreased circulating alanine transaminase level J:175295
decreased circulating aspartate transaminase level J:175295
decreased circulating cholesterol level J:175295
decreased circulating HDL cholesterol level J:175295
decreased circulating iron level J:175295
decreased circulating LDL cholesterol level J:175295
decreased circulating serum albumin level J:175295
decreased circulating total protein level J:175295
decreased total body fat amount J:175295
increased blood urea nitrogen level J:175295
increased hemoglobin content J:175295
increased mean corpuscular hemoglobin J:175295
Ltbp1tm1Rawe/Ltbp1tm1Rawe
B6.129X1-Ltbp1tm1Rawe 		abnormal cranium morphology J:133255
abnormal jaw morphology J:133255
abnormal lower incisor morphology J:133255
liver fibrosis J:133255
short mandible J:133255
short maxilla J:133255
short snout J:133255
small basioccipital bone J:133255
small basisphenoid bone J:133255
Ltbp1tm1Veto/Ltbp1tm1Veto
involves: 129 * C57BL/6 		abnormal cardiac neural crest cell morphology J:128012
abnormal coronary artery morphology J:128012
abnormal fourth pharyngeal arch artery morphology J:128012
abnormal truncus arteriosus septation J:128012
abnormal vascular smooth muscle morphology J:128012
common atrium J:128012
cyanosis J:128012
interrupted aortic arch J:128012
lethality throughout fetal growth and development, incomplete penetrance J:128012
neonatal lethality, complete penetrance J:128012
perimembraneous ventricular septal defect J:128012
persistent truncus arteriosus J:128012
right aortic arch J:128012
Ltbp1tm1Vlcg/Ltbp1tm1Vlcg
involves: 129S/SvEv * C57BL/6 * FVB/N 		normal integument phenotype J:228706
Ltbp1tm2Veto/Ltbp1tm2Veto
involves: 129 * C57BL/6 		abnormal ascending aorta and coronary artery attachment J:128012
abnormal cardiac neural crest cell morphology J:128012
abnormal fourth pharyngeal arch artery morphology J:128012
abnormal truncus arteriosus septation J:128012
abnormal vascular smooth muscle morphology J:128012
common atrium J:128012
cyanosis J:128012
interrupted aortic arch J:128012
lethality throughout fetal growth and development, incomplete penetrance J:128012
neonatal lethality, complete penetrance J:128012
perimembraneous ventricular septal defect J:128012
persistent truncus arteriosus J:128012
right aortic arch J:128012
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory