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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Isl2
insulin related protein 2 (islet 2)
MGI:109156
10 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Isl2tm3.1(Mnx1-Lhx3)Slp/Isl2+
Not Specified 		abnormal axon morphology J:63774, J:122940
abnormal motor neuron innervation pattern J:63774
abnormal motor neuron morphology J:63774
neonatal lethality, complete penetrance J:63774
respiratory failure J:63774
Isl2tm3.1(Mnx1-Lhx3)Slp/Isl2+
Tg(Mnx1-GFP)1Slp/?
Not Specified 		abnormal motor neuron morphology J:122940
Mnx1tm1Jhk/Mnx1tm1Jhk
Isl2tm2Slp/Isl2tm2Slp
involves: 129P2/OlaHsd * 129S1/Sv 		abnormal axon guidance J:89755
abnormal motor neuron innervation pattern J:89755
abnormal motor neuron morphology J:89755
Mnx1tm4(cre)Tmj/Mnx1+
Isl2tm1Arbr/Isl2+
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal motor neuron morphology J:69623, J:76364
Nrg1tm1Cbm/Nrg1tm3Cbm
Isl2tm1Arbr/Isl2+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J 		abnormal motor neuron innervation pattern J:69623
abnormal motor neuron morphology J:69623
abnormal nervous system development J:69623
abnormal neuromuscular synapse morphology J:69623
absent Schwann cells J:69623
neonatal lethality, incomplete penetrance J:69623
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/15/2024
MGI 6.24 		The Jackson Laboratory