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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mnx1
motor neuron and pancreas homeobox 1
MGI:109160
22 phenotypes from 6 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mnx1tm1Jhk/Mnx1tm1Jhk
involves: 129P2/OlaHsd 		abnormal pancreas development J:57314
abnormal pancreatic beta cell physiology J:57314
abnormal pancreatic delta cell morphology J:57314
abnormal pancreatic islet morphology J:57314
decreased fetal size J:57314
decreased pancreatic beta cell number J:57314
normal immune system phenotype J:57314
neonatal lethality, complete penetrance J:57314
small pancreatic islets J:57314
Mnx1tm1Jhk/Mnx1tm1Jhk
involves: 129S1/Sv 		abnormal axon guidance J:89755
abnormal innervation J:89755
Mnx1tm1Slp/Mnx1tm1Slp
involves: BALB/c * C57BL/6 		no abnormal phenotype detected J:152526
Mnx1tm1Tmj/Mnx1tm1Tmj
involves: 129S1/Sv 		abnormal axon morphology J:57340
abnormal duodenum morphology J:57317
abnormal motor neuron morphology J:57340
abnormal pancreas development J:57317
abnormal pancreatic islet morphology J:57317
decreased pancreatic beta cell number J:57317
decreased pancreatic delta cell number J:57317
neonatal lethality, complete penetrance J:57340
normal nervous system phenotype J:57340
primary atelectasis J:57340
thin diaphragm muscle J:57340
Mnx1tm2Tmj/Mnx1tm2Tmj
involves: 129S1/Sv 		abnormal axon morphology J:57340
abnormal hypoglossal nerve morphology J:57340
abnormal motor neuron morphology J:57340
neonatal lethality, complete penetrance J:57340
normal nervous system phenotype J:57340
primary atelectasis J:57340
thin diaphragm muscle J:57340
Mnx1tm3Tmj/Mnx1tm3Tmj
involves: 129S1/Sv 		abnormal axon morphology J:57340
abnormal motor neuron morphology J:57340
neonatal lethality, complete penetrance J:57340
normal nervous system phenotype J:57340
primary atelectasis J:57340
thin diaphragm muscle J:57340
Mnx1tm4(cre)Tmj/Mnx1+
involves: 129S1/Sv 		abnormal neuromuscular synapse morphology J:193844
decreased skeletal muscle fiber size J:193844
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory