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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Grk5
G protein-coupled receptor kinase 5
MGI:109161
15 phenotypes from 4 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Grk5tm1b(KOMP)Mbp/Grk5tm1b(KOMP)Mbp
C57BL/6N-Grk5tm1b(KOMP)Mbp/Ucd
abnormal kidney morphology J:211773
decreased body length J:211773
Grk5tm1Dgen/Grk5tm1Dgen
involves: 129P2/OlaHsd * C57BL/6
increased thermal nociceptive threshold J:101679
Grk5tm1Rjl/Grk5tm1Rjl
involves: 129S4/SvJaeSor
cardiac hypertrophy J:212635
decreased response of heart to induced stress J:212635
Grk5tm1Rjl/Grk5tm1Rjl
involves: 129S4/SvJaeSor * C57BL/6
abnormal CNS synaptic transmission J:59179
abnormal muscle contractility J:96208
decreased body temperature J:59179
decreased core body temperature J:59179
decreased locomotor activity J:59179
decreased thermal nociceptive threshold J:59179
increased airway responsiveness J:96208
increased salivation J:59179
tremors J:59179
Grk5tm2Rjl/Grk5+
B6.129S4-Grk5tm2Rjl
no abnormal phenotype detected J:152746
Grk5tm2Rjl/Grk5tm2Rjl
Tg(Myh6-cre)2182Mds/0
involves: 129S4/SvJaeSor * C57BL/6J * FVB/N
cardiac hypertrophy J:212635
decreased response of heart to induced stress J:212635

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory