Dspp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dspp
dentin sialophosphoprotein
MGI:109172

33 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dspp^{tm1.1(KOMP)Vlcg}/Dspp^{tm1.1(KOMP)Vlcg} C57BL/6N-Dspp^{tm1.1(KOMP)Vlcg}/Ucd	abnormal kidney morphology	J:211773
	improved glucose tolerance	J:211773
	polycystic kidney	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Dspp^tm1Kul/Dspp^tm1Kul B6;129-Dspp^tm1Kul/Mmnc	abnormal alveolar process morphology	J:241990
	abnormal cementum morphology	J:241990
	abnormal junctional epithelium morphology	J:241990
	abnormal osteocyte canaliculus morphology	J:241990
	abnormal osteocyte lacuna morphology	J:241990
	abnormal periodontal ligament morphology	J:241990
	abnormal periodontium morphology	J:241990
	alveolar process atrophy	J:241990
	detached junctional epithelium	J:241990
	periodontal pocket	J:241990
	periodontium inflammation	J:241990
Dspp^tm1Kul/Dspp^tm1Kul involves: 129/Sv * C57BL/6	abnormal branching involved in alveolar duct morphogenesis	J:113417
	abnormal dental pulp cavity morphology	J:84378
	abnormal dentin mineralization	J:84378
	abnormal dentin morphology	J:84378
	abnormal kidney development	J:113417
	abnormal lung development	J:113417
	abnormal metanephric ureteric bud development	J:113417
	abnormal nephron morphogenesis	J:113417
	abnormal predentin morphology	J:84378
	abnormal S-shaped body morphology	J:113417
	abnormal tooth morphology	J:84378
	alveolar process atrophy	J:84378
	brittle teeth	J:84378
	increased kidney apoptosis	J:113417
	small metanephros	J:113417
Tg(Amelx-Dspp)13Mlp/Tg(Amelx-Dspp)13Mlp involves: C57BL/6J * CBA/J * DBA/2J	abnormal enamel morphology	J:101218, J:120871
	abnormal enamel rod pattern	J:101218, J:120871
	enamel pits	J:101218
	reduced enamel thickness	J:120871
Tg(Amelx-Dspp)214Mlp/Tg(Amelx-Dspp)214Mlp involves: C57BL/6J * CBA/J * DBA/2J	abnormal enamel morphology	J:120871

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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