Dsc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dsc1
desmocollin 1
MGI:109173

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dsc1^tm1Dga/Dsc1^tm1Dga involves: C57BL/6J	abnormal epidermal layer morphology	J:73102
	abnormal epidermis stratum corneum morphology	J:73102
	abnormal epidermis stratum spinosum morphology	J:73102
	abnormal keratinocyte differentiation	J:73102
	abnormal snout skin morphology	J:73102
	acantholysis	J:73102
	alopecia	J:73102
	normal behavior/neurological phenotype	J:73102
	cornea opacity	J:73102
	decreased body weight	J:73102
	dermal cyst	J:73102
	dermatitis	J:73102
	disheveled coat	J:73102
	epidermal hyperplasia	J:73102
	eyelids open at birth	J:73102
	failure of eyelid fusion	J:73102
	flaky skin	J:73102
	hair follicle comedo	J:73102
	hair follicle degeneration	J:73102
	hyperkeratosis	J:73102
	impaired skin barrier function	J:73102
	microphthalmia	J:73102
	parakeratosis	J:73102
	skin lesions	J:73102
	thick epidermis	J:73102
Dsc1^tm1Pko/Dsc1^tm1Pko involves: 129S7/SvEvBrd	normal integument phenotype	J:87593
Dsc1^tm1Pko/Dsc1^tm1Pko involves: 129S7/SvEvBrd	no abnormal phenotype detected	J:87593

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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