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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cd59a
CD59a antigen
MGI:109177
32 phenotypes from 2 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cd59atm1Bpm/Cd59atm1Bpm
B6.129-Cd59atm1Bpm
abnormal CD4-positive, alpha-beta T cell physiology J:119703, J:123582
abnormal complement pathway J:92414
abnormal humoral immune response J:119703
choroidal neovascularization J:143638
decreased B cell proliferation J:119703
decreased grip strength J:113567
decreased IgG level J:119703
decreased plasma cell number J:119703
decreased susceptibility to Poxviridae infection J:122201
increased CD4-positive, alpha-beta T cell number J:123582
increased double-positive T cell number J:123582
increased neutrophil cell number J:123582
increased renal tubule apoptosis J:92414
increased susceptibility to experimental autoimmune myasthenia gravis J:113567
increased susceptibility to kidney reperfusion injury J:92414
increased susceptibility to Orthomyxoviridae infection J:123582
increased T cell proliferation J:122201
lung inflammation J:123582
myositis J:113567
pulmonary fibrosis J:123582
Cd59atm1Bpm/Cd59atm1Bpm
involves: 129
abnormal complement pathway J:148367
abnormal Wallerian degeneration J:148367
increased macrophage cell number J:148367
increased susceptibility to induced arthritis J:146711
increased susceptibility to injury J:148367
Cd59atm1Bpm/Cd59atm1Bpm
involves: 129 * BALB/c
increased susceptibility to Orthomyxoviridae infection J:123582
increased susceptibility to weight loss J:123582
Cd59atm1Bpm/Cd59atm1Bpm
involves: 129 * C57BL/6
demyelination J:89014
increased susceptibility to experimental autoimmune encephalomyelitis J:89014
Cd59atm1Bpm/Cd59atm1Bpm
involves: 129/Sv * C57BL/6
decreased body weight J:70419
hemoglobinemia J:70419
hemoglobinuria J:70419
increased erythrocyte osmotic fragility J:70419
reticulocytosis J:70419
Cd59atm1Song/Cd59atm1Song
involves: 129S6/SvEvTac
abnormal complement pathway J:76578

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory