Kif21a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kif21a
kinesin family member 21A
MGI:109188

16 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kif21a^tm1.1Ece/Kif21a⁺ involves: 129S1/Sv * 129S4/SvJae	abnormal eye morphology	J:213171
	abnormal oculomotor nerve morphology	J:213171
	blepharoptosis	J:213171
Kif21a^tm1.1Ece/Kif21a^tm1.1Ece involves: 129S1/Sv * 129S4/SvJae	abnormal abducens nerve morphology	J:213171
	abnormal extraocular muscle morphology	J:213171
	abnormal eye morphology	J:213171
	abnormal innervation pattern to muscle	J:213171
	abnormal oculomotor nerve morphology	J:213171
	blepharoptosis	J:213171
	decreased motor neuron number	J:213171
Kif21a^tm1.1Ece/Kif21a^tm1.1Ece Tg(Isl1-EGFP)1Slp/0 involves: 129S1/Sv 129S4/SvJae * BALB/c * C57BL/6	abnormal abducens nerve morphology	J:213171
	abnormal axon extension	J:213171
	abnormal axon morphology	J:213171
	abnormal extraocular muscle morphology	J:213171
	abnormal oculomotor nerve morphology	J:213171
	increased neuron apoptosis	J:213171
	thin oculomotor nerve	J:213171
Kif21a^tm1.1Ece/Kif21a^tm3Ece involves: 129S1/Sv * 129S4/SvJae	abnormal extraocular muscle morphology	J:213171
Kif21a^{tm1b(EUCOMM)Hmgu}/Kif21a⁺ C57BL/6N-Kif21a^{tm1b(EUCOMM)Hmgu}/J	decreased fasting circulating glucose level	J:211773
Kif21a^{tm1b(EUCOMM)Hmgu}/Kif21a^{tm1b(EUCOMM)Hmgu} C57BL/6N-Kif21a^{tm1b(EUCOMM)Hmgu}/J	preweaning lethality, complete penetrance	J:211773
Kif21a^tm2Ece/? involves: 129S1/Sv * 129S4/SvJae	no abnormal phenotype detected	J:213171
Kif21a^tm3Ece/Kif21a⁺ involves: 129S1/Sv	no abnormal phenotype detected	J:213171
Kif21a^tm3Ece/Kif21a^tm3Ece involves: 129S1/Sv	neonatal lethality, complete penetrance	J:213171
Kif21a^tm3Ece/Kif21a^tm3Ece involves: 129S1/Sv	normal nervous system phenotype	J:213171

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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