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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fgf14
fibroblast growth factor 14
MGI:109189
37 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fgf12tm1Gol/Fgf12tm1Gol
Fgf14tm1Dor/Fgf14tm1Dor
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 		abnormal channel response J:128732
abnormal CNS synaptic transmission J:128732
abnormal gait J:128732
abnormal response to new environment J:128732
ataxia J:128732
decreased grip strength J:128732
hyperactivity J:128732
weakness J:128732
Tg(Camk2a-tTA)1Mmay/0
Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+
involves: 129/Sv * C57BL/6 * CBA * FVB/N 		abnormal dentate gyrus morphology J:185792
hippocampal neuron degeneration J:185792
Tg(Camk2a-tTA)1Mmay/?
Fgf14Tg(tetO-MAPT*P301L)4510Kha/?
involves: 129S6/SvEvTac * FVB/N 		abnormal hippocampus CA1 region morphology J:99626
abnormal neuron morphology J:99626
abnormal spatial learning J:99626
decreased brain weight J:99626
decreased hippocampus pyramidal cell number J:99626
forebrain atrophy J:99626
neurofibrillary tangles J:99626
Tg(Camk2a-tTA)1Mmay/0
Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+
involves: 129S6/SvEvTac * FVB/N 		abnormal anxiety-related response J:207366
decreased anxiety-related response J:207366
impaired contextual conditioning behavior J:207366
impaired cued conditioning behavior J:207366
increased anxiety-related response J:207366
increased exploration in new environment J:207366
increased locomotor activity J:207366
neurofibrillary tangles J:207366
tau protein deposits J:207366
Tg(Camk2a-tTA)1Mmay/0
Fgf14Tg(tetO-MAPT*P301L)4510Kha/Fgf14+
involves: FVB/N 		abnormal corticospinal tract morphology J:102973
abnormal gait J:102973
abnormal spatial reference memory J:102973
abnormal spinal cord morphology J:102973
astrocytosis J:102973
decreased brain weight J:102973
decreased exploration in new environment J:102973
dystonia J:102973
forebrain atrophy J:102973
hippocampal neuron degeneration J:102973
hunched posture J:102973
impaired coordination J:102973
impaired swimming J:102973
limb grasping J:102973
neurofibrillary tangles J:102973
neuron degeneration J:102973
tau protein deposits J:102973
weight loss J:102973
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory