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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tradd
TNFRSF1A-associated via death domain
MGI:109200
14 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Traddtm1.1Mak/Tradd+
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N) 		decreased acute inflammation J:138824
Traddtm1.1Mak/Traddtm1.1Mak
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N) 		abnormal spleen follicular dendritic cell network J:138824
absent spleen germinal center J:138824
decreased acute inflammation J:138824
decreased circulating interleukin-6 level J:138824
decreased inflammatory response J:138824
decreased interleukin-6 secretion J:138824
decreased sensitivity to induced cell death J:138824
Traddtm1.1Mpa/Traddtm1.1Mpa
involves: BALB/cJ * C57BL/6 		abnormal interleukin level J:139030
abnormal spleen germinal center morphology J:139030
decreased circulating tumor necrosis factor level J:139030
decreased IgG level J:139030
decreased physiological sensitivity to xenobiotic J:139030
increased susceptibility to bacterial infection J:139030
Traddtm1.1Mpa/Traddtm1.1Mpa
involves: C57BL/6 		decreased interferon-beta secretion J:136289
Traddtm1.1Zgl/Traddtm1.1Zgl
involves: C57BL/6 * FVB/N 		decreased physiological sensitivity to xenobiotic J:139031
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory