Ddit3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ddit3
DNA-damage inducible transcript 3
MGI:109247

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Ddit3^tm1.1Irt/Ddit3^tm1.1Irt Tagln^tm2(cre)Yec/Tagln⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	decreased susceptibility to atherosclerosis	J:233223
	normal homeostasis/metabolism phenotype	J:233223
Ddit3^tm1.1Irt/Ddit3^tm1.1Irt Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Tg(Mup3-Plau)350-2Eps/? involves: C57BL/6 * DBA	increased hepatocellular carcinoma incidence	J:233146
Ddit3^tm1Dron/Ddit3^tm1Dron Mpz^tm3.1Wra/Mpz^tm3.1Wra involves: 129S2/SvPas * C3H * C57BL/6 * FVB/N	decreased myelin sheath thickness	J:241742
	decreased nerve conduction velocity	J:241742
	dysmyelination	J:241742
	impaired coordination	J:241742
Ddit3^tm1Dron/Ddit3^tm1Dron Tg(Col2a1-rtTA,tetO-COMP)2Jath/0 involves: 129X1/SvJ 129S1/Sv * C57BL/6	decreased inflammatory response	J:233238
Ddit3^tm2.1Dron/Ddit3^tm2.1Dron Sil1^{Gt(RST462)Byg}/Sil1^{Gt(RST462)Byg} involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	ataxia	J:154993
	Purkinje cell degeneration	J:154993
Ddit3^tm2.1Dron/Ddit3^tm2.1Dron Tmtc4^{tm1(KOMP)Vlcg}/Tmtc4^{tm1(KOMP)Vlcg} involves: C57BL/6J * C57BL/6NTac	decreased threshold for auditory brainstem response	J:268046
	impaired hearing	J:268046

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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