Ddit3 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ddit3
DNA-damage inducible transcript 3
MGI:109247

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Ddit3^tm1.1Irt/Ddit3^tm1.1Irt Tagln^tm2(cre)Yec/Tagln⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	decreased susceptibility to atherosclerosis	J:233223
	normal homeostasis/metabolism phenotype	J:233223
Ddit3^tm1.1Irt/Ddit3^tm1.1Irt Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Tg(Mup3-Plau)350-2Eps/? involves: C57BL/6 * DBA	increased hepatocellular carcinoma incidence	J:233146
Ddit3^tm1Dron/Ddit3^tm1Dron Mpz^tm3.1Wra/Mpz^tm3.1Wra involves: 129S2/SvPas * C3H * C57BL/6 * FVB/N	decreased myelin sheath thickness	J:241742
	decreased nerve conduction velocity	J:241742
	dysmyelination	J:241742
	impaired coordination	J:241742
Ddit3^tm1Dron/Ddit3^tm1Dron Tg(Col2a1-rtTA,tetO-COMP)2Jath/0 involves: 129X1/SvJ 129S1/Sv * C57BL/6	decreased inflammatory response	J:233238
Ddit3^tm2.1Dron/Ddit3^tm2.1Dron Sil1^{Gt(RST462)Byg}/Sil1^{Gt(RST462)Byg} involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	ataxia	J:154993
	Purkinje cell degeneration	J:154993
Ddit3^tm2.1Dron/Ddit3^tm2.1Dron Tmtc4^{tm1(KOMP)Vlcg}/Tmtc4^{tm1(KOMP)Vlcg} involves: C57BL/6J * C57BL/6NTac	decreased threshold for auditory brainstem response	J:268046
	impaired hearing	J:268046

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/17/2024 MGI 6.24