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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif 1
MGI:109249
43 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Adamts1em1(IMPC)Mbp/Adamts1+
C57BL/6N-Adamts1em1(IMPC)Mbp/MbpMmucd 		abnormal eye morphology J:211773
abnormal kidney morphology J:211773
abnormal spleen morphology J:211773
enlarged spleen J:211773
eye hemorrhage J:211773
no spontaneous movement J:211773
small kidney J:211773
Adamts1em1(IMPC)Mbp/Adamts1em1(IMPC)Mbp
C57BL/6N-Adamts1em1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal body wall morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
abnormal tail morphology J:211773
no spontaneous movement J:211773
preweaning lethality, incomplete penetrance J:211773
Adamts1tm1Dgen/Adamts1tm1Dgen
involves: 129P2/OlaHsd * C57BL/6J 		abnormal kidney morphology J:82809
enlarged kidney J:82809
hydronephrosis J:82809
increased kidney weight J:82809
kidney cortex atrophy J:82809
Adamts1tm1Hku/Adamts1tm1Hku
involves: 129S6/SvEvTac * C57BL/6 		abnormal adrenal medulla morphology J:62260
abnormal kidney corticomedullary boundary morphology J:62260
abnormal ureter morphology J:62260
abnormal ureteropelvic junction morphology J:62260
absent kidney papilla J:62260
decreased body weight J:62260
decreased litter size J:62260
decreased mature ovarian follicle number J:62260
decreased total body fat amount J:62260
decreased urine chloride ion level J:62260
decreased urine potassium level J:62260
decreased urine sodium level J:62260
dilated kidney calyx J:62260
dilated uterus J:62260
normal homeostasis/metabolism phenotype J:62260
impaired embryo implantation J:62260
kidney papillary hypoplasia J:62260
polyuria J:62260
reduced female fertility J:62260
ureteropelvic junction obstruction J:62260
uterus cyst J:62260
Adamts1tm1Mapr/Adamts1tm1Mapr
involves: 129/Sv * C57BL/6 		abnormal kidney morphology J:96781
decreased litter size J:96781
decreased ovulation rate J:96781
dilated kidney calyx J:96781
kidney cortex atrophy J:96781
kidney medulla atrophy J:96781
perinatal lethality, incomplete penetrance J:96781
postnatal lethality, incomplete penetrance J:96781
reduced female fertility J:96781
Adamts1tm1Mlia/Adamts1tm1Mlia
involves: 129X1/SvJ * BALB/c 		abnormal kidney morphology J:102464
decreased body weight J:102464
perinatal lethality, incomplete penetrance J:102464
ureter obstruction J:102464
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory