Gzmb Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gzmb
granzyme B
MGI:109267

10 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gzmb^{em1(IMPC)Ccpcz}/Gzmb^{em1(IMPC)Ccpcz} C57BL/6NCrl-Gzmb^{em1(IMPC)Ccpcz}/Ccpcz	abnormal behavior	J:211773
Gzmb^tm1Asmv/Gzmb^tm1Asmv involves: C57BL/6	normal immune system phenotype	J:203720
Gzmb^tm1Ley/Gzmb^tm1Ley B6.129S2-Gzmb^tm1Ley	impaired natural killer cell mediated cytotoxicity	J:113213
Gzmb^tm1Ley/Gzmb^tm1Ley involves: 129S2/SvPas * C57BL/6	abnormal enzyme/coenzyme activity	J:113349
Gzmb^tm1Ley/Gzmb^tm1Ley involves: 129S2/SvPas * C57BL/6J	decreased cytotoxic T cell cytolysis	J:23560
Gzmb^tm1Ley/Gzmb^tm1Ley involves: 129X1/SvJ	abnormal NK cell physiology	J:126114
	decreased T cell apoptosis	J:126114
	decreased tumor growth/size	J:126114
	increased susceptibility to induced morbidity/mortality	J:126114
Gzmb^tm2.1Ley/Gzmb^tm2.1Ley 129X1/SvJ-Gzmb^tm2.1Ley	decreased cytotoxic T cell cytolysis	J:96538
Gzmb^tm2Ley/Gzmb^tm2Ley 129X1/SvJ-Gzmb^tm2Ley	abnormal immune system physiology	J:96538
Gzmb^tm2Ley/Gzmb^tm2Ley 129X1/SvJ-Gzmb^tm2Ley	decreased cytotoxic T cell cytolysis	J:96538

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24