Trim28 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trim28
tripartite motif-containing 28
MGI:109274

39 phenotypes from 7 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Nr5a1-cre)2Klp/0 Trim28^tm1.1Ics/Trim28^tm1.1Ipc involves: 129S * 129S2/SvPas * C57BL/6J * DBA/2J	abnormal ovarian follicle morphology	J:327192
Tg(Nr5a1-cre)2Klp/0 Trim28^tm1.1Ipc/Trim28^tm1.1Ipc involves: 129S * 129S2/SvPas * C57BL/6J * DBA/2J	abnormal ovarian follicle morphology	J:327192
	normal cellular phenotype	J:327192
Trim28^chatwo/Trim28^chatwo either: C57BL/6-Trim28^chatwo or (involves: C57BL/6J * FVB/NJ)	abnormal digestive system development	J:178936
	abnormal ectoplacental cavity morphology	J:178936
	abnormal endoderm development	J:178936
	abnormal extraembryonic coelom morphology	J:178936
	abnormal extraembryonic tissue morphology	J:178936
	abnormal lateral plate mesoderm morphology	J:178936
	abnormal parietal yolk sac morphology	J:178936
	abnormal somatic mesoderm morphology	J:178936
	abnormal trophectoderm morphology	J:178936
	delayed allantois development	J:178936
	embryonic growth arrest	J:178936
	embryonic lethality, complete penetrance	J:178936
	open neural tube	J:178936
	short rostral-caudal axis	J:178936
Trim28^chatwo/Trim28^tm1.2Ipc involves: 129S2/SvPas * C57BL/6J	embryonic growth arrest	J:178936
	embryonic lethality, complete penetrance	J:178936
Trim28^MommeD9/Trim28⁺ involves: FVB/N	abnormal sex determination	J:142335
Trim28^MommeD9/Trim28⁺ involves: FVB/N	decreased litter size	J:142335
Trim28^MommeD9/Trim28^MommeD9 involves: FVB/N	embryonic growth arrest	J:142335
Trim28^MommeD9/Trim28^MommeD9 involves: FVB/N	embryonic lethality, complete penetrance	J:142335
Trim28^tm1.1Ics/Trim28^tm1.1Ics involves: 129S * C57BL/6J	prenatal lethality, complete penetrance	J:327192
Trim28^tm1.1Ipc/Trim28^tm1.1Ipc Plekha5^{Tg(AMH-cre)1Flor}/Plekha5⁺ involves: 129S2/SvPas * C57BL/6 * SJL	abnormal spermatid morphology	J:170392
	abnormal spermiation	J:170392
	decreased litter size	J:170392
	decreased male germ cell number	J:170392
	decreased testis weight	J:170392
	oligozoospermia	J:170392
	reduced male fertility	J:170392
	normal reproductive system phenotype	J:170392
	testis degeneration	J:170392
Trim28^tm1.1Ipc/Trim28^tm1.2Ipc Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S2/SvPas * C57BL/6 * CBA	abnormal digestive system development	J:178936
	abnormal lateral plate mesoderm morphology	J:178936
	abnormal vitelline vasculature morphology	J:178936
	normal embryo phenotype	J:178936
	embryonic growth arrest	J:178936
	short rostral-caudal axis	J:178936
	wavy neural tube	J:178936
Trim28^tm1.2Ipc/Trim28^tm1.2Ipc involves: 129S2/SvPas * C57BL/6	abnormal endoderm development	J:62628
	abnormal extraembryonic endoderm formation	J:62628
	absent mesoderm	J:62628
	embryonic lethality between implantation and somite formation, complete penetrance	J:62628
Trim28^tm1Fca/Trim28^tm1.1Ipc Plekha5^{Tg(AMH-cre)1Flor}/Plekha5⁺ involves: 129S2/SvPas * C57BL/6 * SJL	normal reproductive system phenotype	J:170392
Trim28^tm1Fca/Trim28^tm1Fca Not Specified	abnormal cell cycle	J:170392
	abnormal embryo turning	J:170392
	abnormal neural tube closure	J:170392
	embryonic growth retardation	J:170392
	embryonic lethality during organogenesis, complete penetrance	J:170392
Trim28^tm1Ipc/Trim28⁺ involves: 129S2/SvPas * C57BL/6	no abnormal phenotype detected	J:62628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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