Slpi Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slpi
secretory leukocyte peptidase inhibitor
MGI:109297

11 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slpi^tm1Ktak/Slpi^tm1Ktak B6.129P2-Slpi^tm1Ktak	increased susceptibility to bacterial infection	J:132933
Slpi^tm1Ktak/Slpi^tm1Ktak B6.129P2-Slpi^tm1Ktak	increased susceptibility to induced morbidity/mortality	J:132933
Slpi^tm1Nkw/Slpi^tm1Nkw involves: 129P2/OlaHsd * C57BL/6	abnormal macrophage physiology	J:82214
	increased B cell proliferation	J:82214
	increased interleukin-6 secretion	J:82214
	increased susceptibility to endotoxin shock	J:82214
Slpi^tm1Smw/Slpi^tm1Smw involves: 129S1/Sv * 129X1/SvJ	abnormal platelet physiology	J:95293
Slpi^tm1Smw/Slpi^tm1Smw involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal wound healing	J:65241
	delayed wound healing	J:65241
	impaired wound healing	J:65241
	increased transforming growth factor beta level	J:65241

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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