Fadd Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fadd
Fas associated via death domain
MGI:109324

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cyld^tm1.1Mpa/Cyld^tm1.1Mpa Fadd^tm1Mpa/Fadd^tm1Mpa Tg(Vil1-cre)997Gum/0 B6.Cg-Fadd^tm1Mpa Cyld^tm1.1Mpa Tg(Vil1-cre)997Gum	cecum inflammation	J:175865
	decreased Paneth cell number	J:175865
	normal digestive/alimentary phenotype	J:175865
Fadd^tm1Mpa/Fadd^tm1Mpa Ikbkg^tm1.1Mpa/Ikbkg^tm1.1Mpa Tg(Alb1-cre)7Gsc/0 involves: C57BL/6 * FVB/N	abnormal enzyme/coenzyme activity	J:118336
	decreased apoptosis	J:118336
	decreased circulating alanine transaminase level	J:118336
	liver inflammation	J:118336
	normal liver/biliary system phenotype	J:118336
Fadd^tm1Mpa/Fadd^tm1Mpa Mlkl^tm1.1Wsa/Mlkl^tm1.1Wsa Otulin^{tm1c(EUCOMM)Hmgu}/Otulin^{tm1c(EUCOMM)Hmgu} Tg(KRT14-cre)1Cgn/0 involves: C57BL/6 * C57BL/6N * DBA/2	normal immune system phenotype	J:312394
	normal integument phenotype	J:312394
Fadd^tm1Mpa/Fadd^tm1Mpa Myd88^tm1Aki/Myd88^tm1Aki Tg(Vil1-cre)997Gum/0 B6.Cg-Fadd^tm1Mpa Myd88^tm1Aki Tg(Vil1-cre)997Gum	cecum inflammation	J:175865
	decreased Paneth cell number	J:175865
	normal digestive/alimentary phenotype	J:175865
Fadd^tm1Mpa/Fadd^tm1Mpa Ripk3^tm1Vmd/Ripk3^tm1Vmd Tg(Vil1-cre)997Gum/0 B6.Cg-Fadd^tm1Mpa Ripk3^tm1Vmd Tg(Vil1-cre)997Gum	normal digestive/alimentary phenotype	J:175865
	normal mortality/aging	J:175865
Fadd^tm1Mpa/Fadd^tm1Mpa Tnf^tm1Gkl/Tnf^tm1Gkl Tg(Vil1-cre)997Gum/0 B6.Cg-Fadd^tm1Mpa Tnf^tm1Gkl Tg(Vil1-cre)997Gum	cecum inflammation	J:175865
	colitis	J:175865
	decreased Paneth cell number	J:175865
Fadd^tm1Wnt/Fadd^tm1Wnt Tg(Fadd)33Wnt/0 involves: 129S4/SvJae * C57BL/6 * CBA	normal immune system phenotype	J:69617
Fadd^tm1Wnt/Fadd^tm1Wnt Tg(Fadd)33Wnt/0 Tg(Lck-cre)I57Jxm/0 involves: 129S4/SvJae * C57BL/6 * CBA * ICR	abnormal T cell differentiation	J:69617
	decreased CD4-positive, alpha-beta T cell number	J:69617
	decreased CD8-positive, alpha-beta T cell number	J:69617
	decreased double-positive T cell number	J:69617
	increased B cell number	J:69617
	increased double-negative T cell number	J:69617
	thymus hypoplasia	J:69617
Fadd^tm1Wnt/Fadd^tm1Wnt Tg(Fadd)33Wnt/0 Tg(Lck-cre)I57Jxm/0 Tg(Tcra2C,Tcrb2C)1Dlo/0 involves: 129S4/SvJae * C57BL/6 * C57L * CBA * ICR * SJL	increased double-negative T cell number	J:69617
	thymus hypoplasia	J:69617

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24