About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prop1
paired like homeodomain factor 1
MGI:109330
44 phenotypes from 3 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Prop1df/Prop1df
DF 		abnormal granulosa cell morphology J:307483
abnormal ovarian follicle morphology J:307483
abnormal pituitary gland development J:108961
abnormal pituitary gland morphology J:108961
decreased body size J:108961
decreased primary ovarian follicle number J:307483
decreased secondary ovarian follicle number J:307483
decreased tertiary ovarian follicle number J:307483
increased primordial ovarian follicle number J:307483
pituitary gland hypoplasia J:108961
Prop1df/Prop1df
involves: C57BL/6J 		normal endocrine/exocrine gland phenotype J:94409
premature death J:94409
Prop1df/Prop1df
Not Specified 		abnormal enzyme/coenzyme activity J:84401
Prop1df/Prop1df
STOCK Prop1df 		absent corpus luteum J:12169
absent somatotrophs J:7211
absent tertiary ovarian follicles J:12169
decreased circulating follicle stimulating hormone level J:5900
decreased circulating growth hormone level J:6340
decreased circulating prolactin level J:5900
decreased circulating thyroid-stimulating hormone level J:6340
decreased follicle stimulating hormone level J:5900
decreased luteinizing hormone level J:5900
decreased thyrotroph cell number J:12169
normal endocrine/exocrine gland phenotype J:12169
female infertility J:36967
male infertility J:36967
proportional dwarf J:36967
small adenohypophysis J:12169
small ovary J:12169
small thyroid gland J:12169
Prop1tm1Rsd/Prop1tm1Rsd
involves: 129S1/Sv * 129X1/SvJ 		abnormal adenohypophysis development J:114817
Prop1tm1Sac/Prop1+
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J 		abnormal pituitary gland morphology J:94409
Prop1tm1Sac/Prop1tm1Sac
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J 		abnormal neurohypophysis morphology J:94409
abnormal pulmonary alveolus morphology J:94409
abnormal respiratory system physiology J:94409
abnormal surfactant secretion J:94409
adenohypophysis hypoplasia J:94409
atelectasis J:94409
cyanosis J:94409
hypopituitarism J:94409
increased circulating corticosterone level J:94409
lethargy J:94409
neonatal lethality, incomplete penetrance J:94409
pituitary gland hypoplasia J:94409
postnatal lethality, incomplete penetrance J:94409
premature death J:94409
proportional dwarf J:94409
respiratory distress J:94409
small gonad J:94409
small thyroid gland J:94409
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory