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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prop1
paired like homeodomain factor 1
MGI:109330
44 phenotypes from 3 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Prop1df/Prop1df
DF 		abnormal granulosa cell morphology J:307483
abnormal ovarian follicle morphology J:307483
abnormal pituitary gland development J:108961
abnormal pituitary gland morphology J:108961
decreased body size J:108961
decreased primary ovarian follicle number J:307483
decreased secondary ovarian follicle number J:307483
decreased tertiary ovarian follicle number J:307483
increased primordial ovarian follicle number J:307483
pituitary gland hypoplasia J:108961
Prop1df/Prop1df
involves: C57BL/6J 		normal endocrine/exocrine gland phenotype J:94409
premature death J:94409
Prop1df/Prop1df
Not Specified 		abnormal enzyme/coenzyme activity J:84401
Prop1df/Prop1df
STOCK Prop1df 		absent corpus luteum J:12169
absent somatotrophs J:7211
absent tertiary ovarian follicles J:12169
decreased circulating follicle stimulating hormone level J:5900
decreased circulating growth hormone level J:6340
decreased circulating prolactin level J:5900
decreased circulating thyroid-stimulating hormone level J:6340
decreased follicle stimulating hormone level J:5900
decreased luteinizing hormone level J:5900
decreased thyrotroph cell number J:12169
normal endocrine/exocrine gland phenotype J:12169
female infertility J:36967
male infertility J:36967
proportional dwarf J:36967
small adenohypophysis J:12169
small ovary J:12169
small thyroid gland J:12169
Prop1tm1Rsd/Prop1tm1Rsd
involves: 129S1/Sv * 129X1/SvJ 		abnormal adenohypophysis development J:114817
Prop1tm1Sac/Prop1+
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J 		abnormal pituitary gland morphology J:94409
Prop1tm1Sac/Prop1tm1Sac
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J 		abnormal neurohypophysis morphology J:94409
abnormal pulmonary alveolus morphology J:94409
abnormal respiratory system physiology J:94409
abnormal surfactant secretion J:94409
adenohypophysis hypoplasia J:94409
atelectasis J:94409
cyanosis J:94409
hypopituitarism J:94409
increased circulating corticosterone level J:94409
lethargy J:94409
neonatal lethality, incomplete penetrance J:94409
pituitary gland hypoplasia J:94409
postnatal lethality, incomplete penetrance J:94409
premature death J:94409
proportional dwarf J:94409
respiratory distress J:94409
small gonad J:94409
small thyroid gland J:94409
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory