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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Etv6
ets variant 6
MGI:109336
10 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Etv6tm1(RUNX1)Haho/Etv6+
Runx1tm3Spe/Runx1+
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * CBA 		increased hematopoietic stem cell number J:151639
Etv6tm1(RUNX1)Haho/Etv6+
Runx1tm3Spe/Runx1tm3Spe
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * CBA 		anemia J:151639
decreased hematopoietic stem cell number J:151639
premature death J:151639
Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J 		preweaning lethality, incomplete penetrance J:174866
Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J 		increased leukemia incidence J:174866
Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+
TgTn(sb-T2/Onc)76Dla/0
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N 		increased leukemia incidence J:174866
premature death J:174866
Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6tm1.1(RUNX1,hsb5)Lvdw
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J 		embryonic lethality during organogenesis, complete penetrance J:174866
Etv6tm3(NTRK3)Sho/Etv6+
involves: 129S1/Sv 		increased mammary gland tumor incidence J:130323
Etv6tm3(NTRK3)Sho/Etv6+
Tg(Wap-cre)11738Mam/0
involves: 129S1/Sv * C57BL/6 * SJL 		increased mammary gland tumor incidence J:130323
mammary gland alveolar hyperplasia J:130323
Etv6tm3(NTRK3)Sho/Etv6+
Tg(MMTV-cre)FMam/0
involves: 129S1/Sv * FVB/N 		increased chronic myelocytic leukemia incidence J:130323
premature death J:130323
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory