Eya1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Eya1
EYA transcriptional coactivator and phosphatase 1
MGI:109344

44 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Eya1^bor/Eya1^bor Nxf1^Mvb1/Nxf1⁺ involves: C3HeB/FeJ * C57BL/6J * CAST/Ei	increased or absent threshold for auditory brainstem response	J:86371
Eya1^bor/Eya1^bor Nxf1^Mvb1/Nxf1^Mvb1 involves: C3HeB/FeJ * C57BL/6J * CAST/Ei	abnormal cochlear ganglion morphology	J:86371
	circling	J:86371
	head bobbing	J:86371
	increased or absent threshold for auditory brainstem response	J:86371
	normal renal/urinary system phenotype	J:86371
Eya1^tm1Rilm/Eya1⁺ Pax2^tm1Pgr/Pax2⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal semicircular canal ampulla morphology	J:119574
	abnormal semicircular canal morphology	J:119574
	abnormal vestibular saccule morphology	J:119574
	decreased cochlea coiling	J:119574
	decreased lateral semicircular canal size	J:119574
	decreased posterior semicircular canal size	J:119574
	decreased superior semicircular canal size	J:119574
	short endolymphatic duct	J:119574
	small vestibular saccule	J:119574
Eya1^tm1Rilm/Eya1⁺ Pax2^tm1Pgr/Pax2⁺ Six1^tm1Mair/Six1⁺ involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal semicircular canal ampulla morphology	J:119574
	abnormal semicircular canal morphology	J:119574
	abnormal vestibular saccule morphology	J:119574
	decreased cochlea coiling	J:119574
	decreased lateral semicircular canal size	J:119574
	decreased posterior semicircular canal size	J:119574
	decreased superior semicircular canal size	J:119574
	short endolymphatic duct	J:119574
	small vestibular saccule	J:119574
Eya1^tm1Rilm/Eya1⁺ Tbx1^tm1Bem/Tbx1⁺ involves: 129 * C57BL/6 * CD-1 * SJL	abnormal cardiovascular development	J:172023
Eya1^tm1Rilm/Eya1⁺ Six1^tm1Mair/Six1⁺ involves: 129/Sv * 129S1/Sv * 129X1/SvJ	abnormal ureteric bud morphology	J:83432
	absent kidney	J:83432
	impaired branching involved in ureteric bud morphogenesis	J:83432
	renal hypoplasia	J:83432
	single kidney	J:83432
Eya1^tm1Rilm/Eya1⁺ Six1^tm1Mair/Six1⁺ involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal ureteric bud morphology	J:83432
	impaired branching involved in ureteric bud morphogenesis	J:83432
	renal hypoplasia	J:83432
	single kidney	J:83432
Eya1^tm1Rilm/Eya1⁺ Six1^tm1Mair/Six1⁺ involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cochlea morphology	J:119574
	abnormal inner ear morphology	J:119574
	abnormal semicircular canal ampulla morphology	J:119574
	abnormal semicircular canal morphology	J:119574
	abnormal vestibular saccule morphology	J:119574
	decreased cochlea coiling	J:119574
	decreased lateral semicircular canal size	J:119574
	decreased posterior semicircular canal size	J:119574
	decreased superior semicircular canal size	J:119574
	short endolymphatic duct	J:119574
Eya1^tm1Rilm/Eya1⁺ Six1^tm1Mair/Six1^tm1Mair involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiac outflow tract development	J:172023
	abnormal common carotid artery morphology	J:172023
	double outlet right ventricle	J:172023
	retroesophageal right subclavian artery	J:172023
	right aortic arch	J:172023
Eya1^tm1Rilm/Eya1⁺ Six1^tm1Rsd/Six1⁺ involves: 129S1/Sv * 129X1/SvJ	renal hypoplasia	J:86619
	single kidney	J:86619
Eya1^tm1Rilm/Eya1⁺ Sumo1^{Gt(RRQ016)Byg}/Sumo1⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	cleft secondary palate	J:112841
Eya1^tm1Rilm/Eya1^tm1Rilm Six1^tm1Mair/Six1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiac outflow tract development	J:172023
	double outlet right ventricle	J:172023
	interrupted aortic arch	J:172023
	retroesophageal right subclavian artery	J:172023
	vascular ring	J:172023
Eya1^tm1Rilm/Eya1^tm1Rilm Six1^tm1Mair/Six1^tm1Mair involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiac outflow tract development	J:172023
	abnormal craniofacial development	J:172023
	abnormal extraocular muscle morphology	J:172023
	abnormal pulmonary artery morphology	J:172023
	abnormal skeletal muscle morphology	J:172023
	decreased cell proliferation	J:172023
	double outlet right ventricle	J:172023
	facial muscle hypoplasia	J:172023
	increased apoptosis	J:172023
	interrupted aortic arch, type b	J:172023
	persistent truncus arteriosus	J:172023
	retroesophageal right subclavian artery	J:172023
	right aortic arch	J:172023
	tongue muscle hypoplasia	J:172023
	vascular ring	J:172023
Eya1^tm1Rilm/Eya1^tm1Rilm Six1^tm1Rsd/Six1^tm1Rsd involves: 129S1/Sv * 129X1/SvJ	abnormal epaxial muscle morphology	J:86619
	absent hypaxial muscle	J:86619
	absent kidney	J:86619
	pituitary gland hypoplasia	J:86619
	small pituitary gland	J:86619
Eya1^tm1Rilm/Eya1^tm1Rilm Tbx1^tm1Bem/Tbx1⁺ involves: 129 * C57BL/6 * CD-1 * SJL	persistent truncus arteriosus	J:172023

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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