Atf2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atf2
activating transcription factor 2
MGI:109349

29 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atf2^{Tg(Gzma-Klra1)7Wum}/Atf2⁺ involves: C57BL/6	abnormal artery development	J:134875
	abnormal NK cell physiology	J:61178
	decreased circulating interferon-gamma level	J:61178
	decreased NK cell number	J:61178
	decreased NK T cell number	J:61178
	normal immune system phenotype	J:61178
	increased metastatic potential	J:61178
Atf2^tm1Nicj/Atf2^tm1Nicj Atf7^tm1Nicj/Atf7^tm1Nicj involves: 129P2/OlaHsd * C57BL/6	abnormal common myeloid progenitor cell morphology	J:123909
	anemia	J:123909
	embryonic growth arrest	J:123909
	embryonic growth retardation	J:123909
	embryonic lethality during organogenesis, complete penetrance	J:123909
Atf2^tm1Sis/Atf2⁺ Creb5^tm1Sis/Creb5⁺ involves: C57BL/6 * CBA	abnormal cell differentiation	J:156376
	normal adipose tissue phenotype	J:156376
	normal behavior/neurological phenotype	J:156376
	decreased subcutaneous adipose tissue amount	J:156376
	decreased white adipose tissue amount	J:156376
	decreased white fat cell size	J:156376
	normal growth/size/body region phenotype	J:156376
	improved glucose tolerance	J:156376
	increased insulin sensitivity	J:156376
	increased oxygen consumption	J:156376
Atf2^tm1Sis/Atf2^tm1Sis Creb5^tm1Sis/Creb5^tm1Sis involves: C57BL/6 * CBA	abnormal cell differentiation	J:156376
Atf2^tm2Nicj/Atf2^tm2Nicj Atf7^tm1Nicj/Atf7^tm1Nicj involves: 129P2/OlaHsd * C57BL/6	abnormal common myeloid progenitor cell morphology	J:123909
	abnormal liver morphology	J:123909
	anemia	J:123909
	decreased cell proliferation	J:123909
	embryonic growth arrest	J:123909
	embryonic growth retardation	J:123909
	embryonic lethality during organogenesis, complete penetrance	J:123909
	heart hypoplasia	J:123909
	hemopericardium	J:123909
	increased apoptosis	J:123909
	increased hepatocyte apoptosis	J:123909
	liver hypoplasia	J:123909

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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