Ung Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ung
uracil DNA glycosylase
MGI:109352

16 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ung^tm1Mend/Ung^tm1Mend involves: 129S4/SvJae * BALB/c	increased cellular sensitivity to oxidative stress	J:90910
Ung^tm1Mend/Ung^tm1Mend involves: 129S4/SvJae * BALB/c	increased susceptibility to ischemic brain injury	J:90910
Ung^tm1Tld/Ung^tm1Tld involves: 129 * C57BL/6J	no abnormal phenotype detected	J:63056
Ung^tm1Tld/Ung^tm1Tld involves: 129P2/OlaHsd	abnormal base-excision repair	J:197809
	abnormal class switch recombination	J:306598
	abnormal somatic hypermutation frequency	J:155454
	increased sensitivity to induced cell death	J:197809
Ung^tm1Tld/Ung^tm1Tld Not Specified	abnormal class switch recombination	J:79590
	decreased IgG3 level	J:79590
	enlarged lymph nodes	J:85353
	enlarged spleen	J:85353
	enlarged thymus	J:85353
	increased B cell derived lymphoma incidence	J:85353
	increased IgM level	J:79590
	lymphoid hyperplasia	J:85353
	premature death	J:85353
	spleen hyperplasia	J:85353

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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