Lmo4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lmo4
LIM domain only 4
MGI:109360

48 phenotypes from 11 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lmo4^{Gt(RRO142)Byg}/Lmo4⁺ involves: 129P2/OlaHsd * C57BL/6J	enhanced behavioral response to cocaine	J:178212
	induced hyperactivity	J:178212
Lmo4^tm1.1Gng/Lmo4^tm1.1Gng involves: 129X1/SvJ	abnormal embryonic neuroepithelial cell proliferation	J:96957
	abnormal embryonic neuroepithelium morphology	J:96957
	abnormal neural fold elevation formation	J:96957
	decreased embryo size	J:96957
	everted embryonic neuroepithelium	J:96957
	exencephaly	J:96957, J:114626
	eyelids open at birth	J:114626
	incomplete rostral neuropore closure	J:96957
	increased embryonic neuroepithelium apoptosis	J:96957
	prenatal lethality, complete penetrance	J:96957
Lmo4^tm1Gan/Lmo4^tm1Gan involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J	abnormal ear development	J:156733
	abnormal endolymphatic duct morphology	J:156733
	abnormal neural tube closure	J:156733
	abnormal semicircular canal ampulla morphology	J:156733
	absent semicircular canals	J:156733
	acrania	J:156733
	decreased cochlea coiling	J:156733
	exencephaly	J:156733
	perinatal lethality, complete penetrance	J:156733
	small otic vesicle	J:156733
Lmo4^tm1Gan/Lmo4^tm2.1Gan Foxg1^tm1(cre)Skm/Foxg1⁺ involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J	abnormal inner ear morphology	J:156733
	abnormal semicircular canal ampulla morphology	J:156733
	absent semicircular canals	J:156733
Lmo4^tm1Gng/Lmo4^tm1Gng Neurod6^tm1(cre)Kan/? involves: 129X1/SvJ	disorganized barrel cortex	J:111629
Lmo4^tm1Sho/Lmo4^tm1Sho H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ either: (involves: 129/Sv * CD-1) or (involves: 129/Sv * C57BL/6)	normal craniofacial phenotype	J:88168
Lmo4^tm1Slp/Lmo4^tm1Slp Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: 129S1/Sv * C57BL/6 * C57BL/10 * CBA/Ca	abnormal acute inflammation	J:282740
	abnormal gut-associated lymphoid tissue morphology	J:282740
	abnormal lymphocyte physiology	J:282740
	abnormal lymphopoiesis	J:282740
	decreased Peyer's patch number	J:282740
	increased susceptibility to bacterial infection	J:282740
Lmo4^tm1Thr/Lmo4^tm2Thr involves: 129S/SvEv * C57BL/6	abnormal brain development	J:88167
	abnormal cerebral cortex morphology	J:88167
	abnormal neural tube morphology	J:88167
	abnormal nose morphology	J:88167
	acrania	J:88167
	anencephaly	J:88167
	decreased embryo size	J:88167
	exencephaly	J:88167
	normal hematopoietic system phenotype	J:88167
	neonatal lethality, incomplete penetrance	J:88167
	pallor	J:88167
	perinatal lethality, incomplete penetrance	J:88167
Lmo4^tm2.1Gan/Lmo4^tm2.1Gan Foxg1^tm1(cre)Skm/Foxg1⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	abnormal inner ear morphology	J:156733
	abnormal semicircular canal ampulla morphology	J:156733
	absent semicircular canals	J:156733
Lmo4^tm2Sho/Lmo4^tm2Sho either: (involves: 129/Sv * CD-1) or (involves: 129/Sv * C57BL/6)	abnormal cranial nerve morphology	J:88168
	abnormal sphenoid bone morphology	J:88168
	abnormal sternocostal joint morphology	J:88168
	abnormal trigeminal nerve morphology	J:88168
	absent presphenoid bone	J:88168
	cervical vertebral fusion	J:88168
	exencephaly	J:88168
	fusion of glossopharyngeal and vagus nerve	J:88168
	neonatal lethality, complete penetrance	J:88168
	open neural tube	J:88168
Lmo4^tm3Sho/Lmo4^tm3Sho either: (involves: 129/Sv * CD-1) or (involves: 129/Sv * C57BL/6)	normal craniofacial phenotype	J:88168

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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