Il10rb Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il10rb
interleukin 10 receptor, beta
MGI:109380

16 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il10rb^{tm1a(KOMP)Wtsi}/Il10rb^{tm1a(KOMP)Wtsi} C57BL/6N-Il10rb^{tm1a(KOMP)Wtsi}/Wtsi	decreased circulating glucose level	J:211773
Il10rb^tm1Agt/Il10rb^tm1Agt involves: 129S2/SvPas * C57BL/6	abnormal crypts of Lieberkuhn morphology	J:45917
	abnormal granulocyte differentiation	J:45917
	abnormal large intestine morphology	J:45917
	abnormal lymph node medullary cord morphology	J:45917
	abnormal mesenteric lymph node morphology	J:45917
	abnormal spleen morphology	J:45917
	colitis	J:134156
	decreased hemoglobin content	J:45917
	extramedullary hematopoiesis	J:45917
	increased interferon-gamma secretion	J:134156
	increased interleukin-17 secretion	J:134156
	increased leukocyte cell number	J:45917
	increased spleen weight	J:45917
	large intestinal inflammation	J:45917
	spleen hyperplasia	J:45917

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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