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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Casp7
caspase 7
MGI:109383
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Casp3tm1Flv/Casp3tm1Flv
Casp7tm1Flv/Casp7+
B6.129S-Casp3tm1Flv Casp7tm1Flv 		decreased fibroblast apoptosis J:105496
decreased sensitivity to induced cell death J:105496
decreased thymocyte apoptosis J:105496
Casp3tm1Flv/Casp3tm1Flv
Casp7tm1Flv/Casp7tm1Flv
B6.129S-Casp3tm1Flv Casp7tm1Flv 		abnormal heart ventricle morphology J:105496
decreased fibroblast apoptosis J:105496
decreased sensitivity to induced cell death J:105496
decreased thymocyte apoptosis J:105496
dilated heart atrium J:105496
exencephaly J:105496
neonatal lethality, incomplete penetrance J:105496
postnatal lethality, complete penetrance J:105496
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory