Ctcf Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ctcf
CCCTC-binding factor
MGI:109447

31 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ctcf^em1Hyao/Ctcf⁺ C57BL/6N-Ctcf^em1Hyao	normal behavior/neurological phenotype	J:350502
	decreased growth hormone level	J:350502
	impaired exercise endurance	J:350502
	normal mortality/aging	J:350502
	thin body	J:350502
Ctcf^em1Hyao/Ctcf^em1Hyao C57BL/6N-Ctcf^em1Hyao	abnormal lung interstitium morphology	J:350502
	abnormal myocardial trabeculae morphology	J:350502
	abnormal nervous system electrophysiology	J:350502
	abnormal neurite morphology	J:350502
	abnormal ventricle myocardium morphology	J:350502
	atelectasis	J:350502
	decreased embryo weight	J:350502
	neonatal lethality, complete penetrance	J:350502
	thick myocardium	J:350502
	thin ventricular wall	J:350502
Ctcf^tm1.1Gfili/Ctcf^tm1.1Gfili involves: 129S4/SvJaeSor * C57BL/6	absent inner cell mass	J:211097
	absent trophectoderm	J:211097
	embryonic growth arrest	J:211097
	embryonic lethality at implantation	J:211097
	increased embryonic tissue cell apoptosis	J:211097
Ctcf^tm2.1Gal/Ctcf⁺ involves: 129P2/OlaHsd * C57BL/6	postnatal lethality, incomplete penetrance	J:143271
Ctcf^tm2.1Gal/Ctcf^tm2.1Gal involves: 129P2/OlaHsd * C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:143271
Ctcf^tm2Gal/Ctcf⁺ Tg(Lck-cre)1Cwi/0 involves: 129P2/OlaHsd * C57BL/6	decreased CD4-positive, alpha-beta T cell number	J:143271
	decreased CD8-positive, alpha-beta T cell number	J:143271
	thymus hypoplasia	J:143271
Ctcf^tm2Gal/Ctcf^tm2Gal Tg(Lck-cre)1Cwi/0 involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:143271
	abnormal T cell morphology	J:143271
	decreased CD4-positive, alpha-beta T cell number	J:143271
	decreased CD8-positive, alpha-beta T cell number	J:143271
	decreased double-positive T cell number	J:143271
	decreased single-positive T cell number	J:143271
	increased double-negative T cell number	J:143271
	increased single-positive T cell number	J:143271
	thymus hypoplasia	J:143271

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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