Ctcf Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ctcf
CCCTC-binding factor
MGI:109447

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ctcf^tm2Gal/Ctcf^tm2Gal Rag2^tm1Fwa/Rag2^tm1Fwa Tg(Lck-cre)1Cwi/0 involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * C57BL/10	decreased double-positive T cell number	J:143271
Ctcf^tm2Gal/Ctcf^tm2Gal Tg(Lck-cre)1Cwi/0 Tg(TcraH-Y,TcrbH-Y)71Vbo/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * DBA/2J	abnormal T cell differentiation	J:143271
	decreased CD4-positive, alpha-beta T cell number	J:143271
	decreased CD8-positive, alpha-beta T cell number	J:143271
	decreased double-positive T cell number	J:143271
Ctcf^tm2Gal/Ctcf^tm2Gal Tg(Lck-cre)1Cwi/0 Tg(TcraTcrb)425Cbn/0 involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:143271
	decreased CD4-positive, alpha-beta T cell number	J:143271
	decreased double-positive T cell number	J:143271
	decreased T cell number	J:143271
	increased double-negative T cell number	J:143271
	increased single-positive T cell number	J:143271

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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