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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Smad1
SMAD family member 1
MGI:109452
46 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2.1Rob
Smad5tm1Huy/Smad5tm1Huy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		early reproductive senescence J:128934
hemoperitoneum J:128934
increased ovarian carcinoma incidence J:128934
increased ovary tumor incidence J:128934
increased testis tumor incidence J:128934
male infertility J:128934
Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2.1Rob
Smad5tm1Huy/Smad5tm1Huy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J 		increased granulosa cell tumor incidence J:157310
premature death J:157310
suppressed circulating follicle stimulating hormone level J:157310
Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Huy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J 		increased granulosa cell tumor incidence J:157310
premature death J:157310
suppressed circulating follicle stimulating hormone level J:157310
Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Zuk
involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 		early reproductive senescence J:128934
hemoperitoneum J:128934
increased ovarian carcinoma incidence J:128934
increased ovary tumor incidence J:128934
increased testis tumor incidence J:128934
male infertility J:128934
Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Zuk
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J 		increased granulosa cell tumor incidence J:157310
premature death J:157310
suppressed circulating follicle stimulating hormone level J:157310
Amhr2tm3(cre)Bhr/Amhr2+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Zuk
Smad9tm1Jfm/Smad9tm1Jfm
involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 		early reproductive senescence J:128934
hemoperitoneum J:128934
increased ovarian carcinoma incidence J:128934
increased ovary tumor incidence J:128934
Bmpr2tm1Mmue/Bmpr2+
Smad1tm1Rjle/Smad1+
involves: 129S1/SvImJ * 129S6/SvEvTac * C57BL/6 		heart right ventricle hypertrophy J:224752
increased right ventricle systolic pressure J:224752
Ltftm1(icre)Tdku/Ltf+
Smad1tm2Rob/Smad1tm2Rob
Smad5tm1Huy/Smad5tm1Huy
involves: 129P2/OlaHsd * 129S/SvEv * 129S6/SvEvTac * C57BL/6 		abnormal decidualization J:324161
abnormal embryo attachment J:324161
abnormal embryo development J:324161
abnormal pregnancy J:324161
abnormal uterine receptivity J:324161
decreased litter size J:324161
delayed embryo implantation J:324161
early reproductive senescence J:324161
female infertility J:324161
impaired embryo implantation J:324161
reduced female fertility J:324161
normal reproductive system phenotype J:324161
Smad1tm1Rob/Smad1+
Smad5tm1Zuk/Smad5+
involves: 129S/SvEv * 129S7/SvEvBrd 		abnormal allantois morphology J:119296
abnormal direction of heart looping J:119296
abnormal forebrain morphology J:119296
abnormal heart development J:119296
abnormal heart looping J:119296
abnormal heart tube morphology J:119296
abnormal left-right axis patterning J:119296
abnormal mesoderm development J:119296
abnormal nervous system development J:119296
abnormal rostral-caudal axis patterning J:119296
abnormal somite development J:119296
absent primordial germ cells J:119296
absent second pharyngeal arch J:119296
absent third pharyngeal arch J:119296
decreased primordial germ cell number J:119296
embryonic lethality during organogenesis, complete penetrance J:119296
excessive folding of visceral yolk sac J:119296
failure of heart looping J:119296
incomplete rostral neuropore closure J:119296
Smad1tm1Rob/Smad1+
Smad5tm1Zuk/Smad5+
Smad9tm2.1Rob/Smad9tm2.1Rob
involves: 129S/SvEv * 129S7/SvEvBrd 		prenatal lethality, complete penetrance J:119296
Smad1tm1Rob/Smad1+
Smad9tm2.1Rob/Smad9tm2.1Rob
involves: 129S/SvEv 		abnormal embryo development J:119296
abnormal embryonic growth/weight/body size J:119296
abnormal embryonic tissue morphology J:119296
abnormal extraembryonic tissue morphology J:119296
abnormal heart development J:119296
abnormal nervous system development J:119296
embryonic lethality during organogenesis J:119296
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11/12/2024
MGI 6.24 		The Jackson Laboratory