Gata5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gata5
GATA binding protein 5
MGI:109497

49 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gata5^tm1.1Nemr/Gata5^tm1.1Nemr Tg(Tagln-cre)1Her/0 involves: C57BL/6 * SJL	normal cardiovascular system phenotype	J:227997
Gata5^tm1.1Nemr/Gata5^tm1.1Nemr Tg(Tek-cre)1Ywa/0 involves: 129 * C57BL/6 * SJL	abnormal aortic valve cusp morphology	J:175663
	bicuspid aortic valve	J:175663
Gata5^tm1.2Nemr/Gata5^tm1.2Nemr involves: 129 * C57BL/6	abnormal aorta bulb morphology	J:175663
	abnormal aortic valve cusp morphology	J:175663
	abnormal blood circulation	J:175663
	abnormal heart development	J:175663
	abnormal heart left ventricle morphology	J:175663
	abnormal heart right ventricle morphology	J:175663
	aorta stenosis	J:175663
	bicuspid aortic valve	J:175663
	decreased fetal cardiomyocyte number	J:175663
	decreased myocardial fiber number	J:175663
	enlarged heart	J:175663
	increased heart left ventricle weight	J:175663
	increased heart right atrium size	J:175663
	increased heart ventricle muscle contractility	J:175663
	increased myocardial fiber size	J:175663
	myocardial trabeculae hypoplasia	J:175663
	thick interventricular septum	J:175663
	thin ventricular wall	J:175663
Gata5^tm1.2Nemr/Gata5^tm1.2Nemr Not Specified	abnormal kidney morphology	J:227997
	abnormal renal glomerulus morphology	J:227997
	abnormal vasodilation	J:227997
	normal behavior/neurological phenotype	J:227997
	decreased renal glomerular filtration rate	J:227997
	decreased renin activity	J:227997
	glomerulosclerosis	J:227997
	hypertension	J:227997
	increased systemic arterial diastolic blood pressure	J:227997
	increased systemic arterial systolic blood pressure	J:227997
	increased urine protein level	J:227997
	kidney inflammation	J:227997
	perivascular fibrosis	J:227997
	salt-sensitive hypertension	J:227997
Gata5^tm1Eem/Gata5^tm1Eem involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal female reproductive system morphology	J:155855
	abnormal renal/urinary system morphology	J:155855
	short perineum	J:155855
Gata5^tm1Eno/Gata5^tm1Eno involves: 129S6/SvEvTac * C57BL/6	abnormal female reproductive system morphology	J:63036
	abnormal female urethra morphology	J:63036
	abnormal perineum morphology	J:63036
	abnormal urethra urothelium morphology	J:63036
	abnormal vagina epithelium morphology	J:63036
	abnormal vagina morphology	J:63036
	abnormal vagina orifice morphology	J:63036
	absent clitoral bone	J:63036
	enlarged clitoris	J:63036
	female preputial gland hypoplasia	J:63036
	perineal fistula	J:63036
	reduced female fertility	J:63036
	short perineum	J:63036
	urethritis	J:63036
	vaginal inflammation	J:63036

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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