Cstb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cstb
cystatin B
MGI:109514

33 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cstb^{tm1b(EUCOMM)Wtsi}/Cstb^{tm1b(EUCOMM)Wtsi} C57BL/6N-Cstb^{tm1b(EUCOMM)Wtsi}/Orl	abnormal auditory brainstem response	J:211773
	abnormal eye anterior chamber depth	J:211773
	abnormal retina outer nuclear layer morphology	J:211773
	decreased body length	J:211773
	decreased circulating creatinine level	J:211773
	decreased lymphocyte cell number	J:211773
	decreased total retina thickness	J:211773
	hyperactivity	J:211773
	increased circulating triglyceride level	J:211773
	increased monocyte cell number	J:211773
	increased vertical activity	J:211773
	short tibia	J:211773
Cstb^tm1Rm/Cstb^tm1Rm either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	abnormal apoptosis	J:50587
	abnormal cornea morphology	J:50587
	abnormal eye physiology	J:50587
	abnormal gait	J:50587
	abnormal nervous system physiology	J:71823
	ataxia	J:50587
	normal behavior/neurological phenotype	J:50587
	cerebellum hypoplasia	J:50587
	cornea opacity	J:50587
	facial muscle spasm	J:50587
	normal growth/size/body region phenotype	J:50587
	impaired coordination	J:50587
	increased incidence of corneal inflammation	J:50587
	myoclonus	J:50587
	uveitis	J:50587
Cstb^tm1Rm/Cstb^tm1Rm involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal brain wave pattern	J:115694
	abnormal cerebellar granule cell morphology	J:115694
	abnormal cerebellum morphology	J:115694
	abnormal cornea morphology	J:115694
	ataxia	J:115694
	cornea scarring	J:115694
	myoclonus	J:115694
	seizures	J:115694
Cstb^tm1Yah/Cstb⁺ B6.129P2-Cstb^tm1Yah	normal behavior/neurological phenotype	J:181132
Cstb^tm1Yah/Cstb⁺ B6.129P2-Cstb^tm1Yah	normal nervous system phenotype	J:181132
Cstb^tm1Yah/Cstb^tm1Yah B6.129P2-Cstb^tm1Yah	normal behavior/neurological phenotype	J:181132
Cstb^tm1Yah/Cstb^tm1Yah B6.129P2-Cstb^tm1Yah	normal nervous system phenotype	J:181132

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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