Sftpb Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sftpb
surfactant associated protein B
MGI:109516

16 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sftpb^tm1Jaw/Sftpb⁺ involves: 129S2/SvPas	abnormal surfactant secretion	J:59460
	decreased lung compliance	J:59460
	decreased total lung capacity	J:59460
	increased susceptibility to injury	J:59460
Sftpb^tm1Jaw/Sftpb^tm1Jaw involves: 129S2/SvPas * Black Swiss	abnormal lipid homeostasis	J:28289
	abnormal pulmonary alveolus morphology	J:28289
	abnormal surfactant composition	J:28289
	abnormal surfactant physiology	J:28289
	abnormal surfactant secretion	J:28289
	abnormal type II pneumocyte morphology	J:28289
	absent alveolar lamellar bodies	J:28289
	atelectasis	J:28289
	cyanosis	J:28289
	neonatal lethality, incomplete penetrance	J:28289
	pup cannibalization	J:28289
	respiratory distress	J:28289
	respiratory failure	J:28289

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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