Trpc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trpc2
transient receptor potential cation channel, subfamily C, member 2
MGI:109527

18 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trpc2^{em1(IMPC)Rbrc}/Trpc2^{em1(IMPC)Rbrc} C57BL/6NJcl-Trpc2^{em1(IMPC)Rbrc}/Rbrc	abnormal brain morphology	J:211773
Trpc2^{Gt(OST448844)Lex}/Trpc2^{Gt(OST448844)Lex} involves: 129S5/SvEvBrd	increased circulating cholesterol level	J:103485
	increased circulating triglyceride level	J:103485
Trpc2^tm1Dlc/Trpc2^tm1Dlc involves: 129S1/Sv	abnormal erythroblast morphology	J:189490
	abnormal erythrocyte physiology	J:189490
	decreased mean corpuscular hemoglobin concentration	J:189490
	increased hematocrit	J:189490
	increased mean corpuscular volume	J:189490
Trpc2^tm1Dlc/Trpc2^tm1Dlc involves: 129S1/Sv * C57BL/6	abnormal accessory olfactory bulb morphology	J:74988
	abnormal mating preference	J:74988
	abnormal nervous system electrophysiology	J:74988
	abnormal sensory neuron innervation pattern	J:74988
	abnormal vomeronasal organ morphology	J:74988
	submission towards male mice	J:74988
Trpc2^tm1Mom/Trpc2^tm1Mom B6.129P2-Trpc2^tm1Mom/Zuf	abnormal behavior	J:279957
Trpc2^tm1Mom/Trpc2^tm1Mom B6.129P2-Trpc2^tm1Mom/Zuf	abnormal vomeronasal sensory neuron physiology	J:279957
Trpc2^tm1Rax/Trpc2^tm1Rax involves: 129S/SvEv	abnormal sexual interaction	J:162636
Trpc2^tm1Rax/Trpc2^tm1Rax involves: 129S/SvEv * C57BL/6J	abnormal mating preference	J:76339
	abnormal nervous system electrophysiology	J:76339
	decreased aggression towards male mice	J:76339
	submission towards male mice	J:76339

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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