E4f1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

E4f1
E4F transcription factor 1
MGI:109530

22 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
E4f1^tm1Pisc/E4f1^tm1.1Llca Polr2a^{tm1(cre/ERT2)Bbd}/Polr2a⁺ involves: 129S4/SvJae * C57BL/6 * SJL	abnormal hair follicle bulge morphology	J:167157
	abnormal keratinocyte physiology	J:167157
	abnormal skin condition	J:167157
	abnormal skin morphology	J:167157
	abnormal skin physiology	J:167157
	absent epidermis stratum granulosum	J:167157
	absent suprabasal layer	J:167157
	alopecia	J:167157
	epidermal hyperplasia	J:167157
	hyperkeratosis	J:167157
	impaired wound healing	J:167157
	spontaneous skin ulceration	J:167157
	thick skin	J:167157
E4f1^tm1Pisc/E4f1^tm1.1Llca Tg(KRT5-cre)5132Jlj/0 involves: 129S4/SvJae * C57BL/6 * DBA/2J	abnormal epidermal layer morphology	J:167157
	abnormal keratinocyte physiology	J:167157
	abnormal skin physiology	J:167157
	absent epidermis stratum granulosum	J:167157
	absent hair follicles	J:167157
	absent suprabasal layer	J:167157
	dehydration	J:167157
	epidermal hyperplasia	J:167157
	hyperkeratosis	J:167157
	postnatal lethality, complete penetrance	J:167157
E4f1^tm1Pisc/E4f1^tm1Pisc involves: 129S4/SvJae * C57BL/6	abnormal apoptosis	J:91435
	abnormal germ layer development	J:91435
	abnormal mitosis	J:91435
	decreased embryo size	J:91435
	embryonic lethality between implantation and somite formation, complete penetrance	J:91435

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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