Cdc37 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdc37
cell division cycle 37
MGI:109531

15 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdc37^em1(IMPC)J/Cdc37⁺ C57BL/6NJ-Cdc37^em1(IMPC)J/Mmjax	hyperactivity	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased startle reflex	J:211773
Cdc37^em1(IMPC)J/Cdc37^em1(IMPC)J C57BL/6NJ-Cdc37^em1(IMPC)J/Mmjax	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to organogenesis, complete penetrance	J:279207
	failure of blastocyst to hatch from the zona pellucida	J:279207
	preweaning lethality, complete penetrance	J:211773
Tg(MMTV-Cdc37)1Stp/0 involves: C57BL/6 * DBA/2 * FVB/N	abnormal mammary gland development	J:62465
	increased lymphoma incidence	J:62465
	increased mammary adenoacanthoma incidence	J:62465
	increased mammary adenocarcinoma incidence	J:62465
	increased tumor incidence	J:62465
Tg(MMTV-Cdc37)2Stp/0 involves: C57BL/6 * DBA/2 * FVB/N	abnormal mammary gland development	J:62465
	increased lymphoma incidence	J:62465
	increased mammary adenoacanthoma incidence	J:62465
	increased sarcoma incidence	J:62465
	increased tumor incidence	J:62465
Tg(Pbsn-Cdc37)1Stp/0 involves: C57BL/6 * DBA/2 * ICR	abnormal prostate gland morphology	J:93695
Tg(Pbsn-Cdc37)1Stp/0 involves: C57BL/6 * DBA/2 * ICR	prostate gland epithelial hyperplasia	J:93695

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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