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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zfpm1
zinc finger protein, multitype 1
MGI:1095400
55 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tg(Gata1-Zfpm1)1Sho/0
Zfpm1tm1Sho/Zfpm1tm1Sho
involves: 129S1/Sv * C57BL/6N * CD-1 		abnormal heart morphology J:99745
atrial septal defect J:99745
atrioventricular septal defect J:99745
common atrioventricular valve J:99745
double outlet right ventricle J:99745
edema J:99745
normal hematopoietic system phenotype J:99745
hemorrhage J:99745
lethality throughout fetal growth and development, complete penetrance J:99745
pallor J:99745
thin myocardium J:99745
ventricular septal defect J:99745
Zfpm1tm1.1Esv/Zfpm1tm1.1Esv
involves: 129S6/SvEvTac * C57BL/6 		abnormal bone marrow cell number J:156475
abnormal common myeloid progenitor cell morphology J:156475
abnormal erythropoiesis J:156475
abnormal megakaryocyte differentiation J:156475
abnormal megakaryocyte progenitor cell morphology J:156475
abnormal spleen morphology J:156475
decreased megakaryocyte cell number J:156475
embryonic lethality during organogenesis, incomplete penetrance J:156475
extramedullary hematopoiesis J:156475
increased erythrocyte cell number J:156475
increased erythroid progenitor cell number J:156475
increased granulocyte number J:156475
increased hemoglobin concentration distribution width J:156475
increased mean platelet volume J:156475
increased neutrophil cell number J:156475
increased spleen red pulp amount J:156475
increased spleen weight J:156475
pale yolk sac J:156475
pericardial edema J:156475
thrombocytopenia J:156475
Zfpm1tm1.1Geab/Zfpm1+
Not Specified 		increased hemoglobin concentration distribution width J:156393
thrombocytopenia J:156393
Zfpm1tm1.1Geab/Zfpm1tm1.1Geab
Not Specified 		abnormal circulating chemokine level J:162629
abnormal erythropoiesis J:156393
abnormal megakaryocyte morphology J:156393
abnormal megakaryocyte progenitor cell morphology J:156393
abnormal platelet morphology J:156393
anemia J:156393
decreased erythroid progenitor cell number J:156393
decreased platelet alpha-granule number J:156393
decreased spleen white pulp amount J:156393
enlarged spleen J:156393
extramedullary hematopoiesis J:156393
normal hematopoietic system phenotype J:156393
increased heart weight J:156393
increased hemoglobin concentration distribution width J:156393
increased mean platelet volume J:156393
increased monocyte cell number J:156393
increased neutrophil cell number J:156393
increased red blood cell distribution width J:156393
increased spleen weight J:156393
lethality throughout fetal growth and development, incomplete penetrance J:156393
perinatal lethality, incomplete penetrance J:156393
reticulocytosis J:156393
spleen hypoplasia J:156393
thrombocytopenia J:156393, J:162629
Zfpm1tm1Sho/Zfpm1tm1Sho
either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6) 		abnormal embryonic erythropoiesis J:47281
abnormal erythropoiesis J:47281
abnormal megakaryocyte differentiation J:47281
abnormal vitelline vasculature morphology J:47281
anemia J:47281
decreased embryo size J:47281
embryonic lethality during organogenesis, complete penetrance J:47281
impaired hematopoiesis J:47281
pale liver J:47281
pale yolk sac J:47281
pallor J:47281
small liver J:47281
Zfpm1tm1Sho/Zfpm1tm1Sho
involves: 129S1/Sv 		abnormal erythropoiesis J:77724
abnormal megakaryocyte progenitor cell morphology J:77724
Zfpm1tm2Sho/Zfpm1tm2Sho
either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6) 		abnormal embryonic erythropoiesis J:47281
abnormal erythropoiesis J:47281
abnormal megakaryocyte differentiation J:47281
abnormal vitelline vasculature morphology J:47281
anemia J:47281
decreased embryo size J:47281
embryonic lethality during organogenesis, complete penetrance J:47281
impaired hematopoiesis J:47281
pale liver J:47281
pale yolk sac J:47281
pallor J:47281
small liver J:47281
Zfpm1tm4Sho/Zfpm1tm4Sho
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6 * CBA 		normal cardiovascular system phenotype J:99745
Zfpm1tm4Sho/Zfpm1tm4Sho
Tg(Gata1-Zfpm1)1Sho/0
Tg(Tek-cre)1Ywa/0
involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL 		atrial septal defect J:99745
atrioventricular septal defect J:99745
common atrioventricular valve J:99745
double outlet right ventricle J:99745
thin myocardium J:99745
ventricular septal defect J:99745
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory