Ptch2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptch2
patched 2
MGI:1095405

20 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptch2^tm1Dgen/Ptch2^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	abnormal bone marrow cell number	J:101679
	abnormal erythrocyte morphology	J:101679
	anemia	J:101679
	decreased hematocrit	J:101679
	decreased hemoglobin content	J:101679
	enlarged spleen	J:101679
	extramedullary hematopoiesis	J:101679
	increased neutrophil cell number	J:101679
Ptch2^tm1Hui/Ptch2⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal dermal layer morphology	J:112169
	alopecia	J:112169
	dermal hyperplasia	J:112169
	epidermal hyperplasia	J:112169
	skin lesions	J:112169
	spontaneous skin ulceration	J:112169
Ptch2^tm1Hui/Ptch2^tm1Hui involves: 129S1/Sv * 129X1/SvJ	alopecia	J:112169
	dermal hyperplasia	J:112169
	epidermal hyperplasia	J:112169
	normal nervous system phenotype	J:112169
	normal reproductive system phenotype	J:112169
	skin lesions	J:112169
	spontaneous skin ulceration	J:112169
Ptch2^tm1Pmc/Ptch2^tm1Pmc involves: 129S1/Sv * C57BL/6	no abnormal phenotype detected	J:112118
Ptch2^{tm3b(EUCOMM)Hmgu}/Ptch2^{tm3b(EUCOMM)Hmgu} C57BL/6N-Ptch2^{tm3b(EUCOMM)Hmgu}/Bay	decreased lymphocyte cell number	J:211773
	enlarged urinary bladder	J:211773
	increased fasting circulating glucose level	J:211773
	increased neutrophil cell number	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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