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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MGI:1095413
60 phenotypes from 6 alleles in 13 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lfngm1Btlr/Lfngm1Btlr
C57BL/6J-Lfngm1Btlr 		kinked tail J:132741
reduced fertility J:132741
short tail J:132741
vertebral fusion J:132741
Lfngtm1.1Dihz/Lfngtm1.1Dihz
involves: 129 * C57BL/6J 		normal embryo phenotype J:184024
normal mortality/aging J:184024
normal skeleton phenotype J:184024
Lfngtm1.2Egan/Lfngtm1.2Egan
FVB.129-Lfngtm1.2Egan 		abnormal lung development J:155893
abnormal lung vasculature morphology J:155893
abnormal pulmonary alveolus morphology J:155893
abnormal rib development J:155893
short tail J:155893
Lfngtm1.2Egan/Lfngtm1.2Egan
involves: 129 * 129S4/SvJaeSor * FVB/N 		abnormal lung development J:155893
abnormal somite development J:155893
impaired lung alveolus development J:155893
prenatal lethality, incomplete penetrance J:155893
Lfngtm1Grid/Lfngtm1Grid
involves: 129S1/Sv 		abnormal retina vasculature morphology J:157345
Lfngtm1Grid/Lfngtm1Grid
involves: 129S1/SvImJ 		abnormal costovertebral joint morphology J:48810
abnormal dorsal-ventral polarity of the somites J:48810
abnormal sternocostal joint morphology J:88580
abnormal thoracic cage morphology J:48810
abnormal vertebrae morphology J:48810
decreased cervical vertebrae number J:88580
decreased rib number J:88580
female infertility J:48810, J:105928
fused dorsal root ganglion J:48810
normal hearing/vestibular/ear phenotype J:62727
neonatal lethality, complete penetrance J:48810
rib bifurcation J:48810
rib fusion J:48810
Lfngtm1Rjo/Lfngtm1Rjo
B6.129S7-Lfngtm1Rjo 		abnormal multifidus muscle morphology J:324821
abnormal rib morphology J:324821
abnormal vertebrae morphology J:324821
rib bifurcation J:324821
rib fusion J:324821
vertebral fusion J:324821
Lfngtm1Rjo/Lfngtm1Rjo
either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * C57BL/6J * FVB/N) 		abnormal lumbar vertebrae morphology J:131837
abnormal rostral-caudal patterning of the somites J:131837
abnormal sacral vertebrae morphology J:131837
abnormal thoracic vertebrae morphology J:131837
male infertility J:131837
postnatal lethality, incomplete penetrance J:131837
rib fusion J:131837
short tail J:131837
Lfngtm1Rjo/Lfngtm1Rjo
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/NJ 		abnormal rib morphology J:149312
decreased caudal vertebrae number J:149312
decreased survivor rate J:149312
postnatal lethality, incomplete penetrance J:149312
Lfngtm1Rjo/Lfngtm1Rjo
involves: 129S7/SvEvBrd 		abnormal rostral-caudal axis patterning J:123846
abnormal sclerotome morphology J:155378
abnormal somite development J:155378
absent caudal vertebrae J:155378
caudal body truncation J:155378
decreased caudal vertebrae number J:155378
decreased survivor rate J:155378
preweaning lethality, incomplete penetrance J:155378
short tail J:155378
Lfngtm1Rjo/Lfngtm1Rjo
involves: 129S7/SvEvBrd * C57BL/6 		abnormal axial skeleton morphology J:48859
abnormal embryo development J:48859
abnormal embryonic hematopoiesis J:146621
abnormal female meiosis J:96967
abnormal female reproductive system morphology J:96967
abnormal gametogenesis J:96967
abnormal oocyte morphology J:96967
abnormal ovarian follicle morphology J:96967
abnormal ovarian folliculogenesis J:96967
abnormal rostral-caudal patterning of the somites J:48859
abnormal vertebrae development J:48859
abnormal vertebral body development J:48859
embryonic lethality, incomplete penetrance J:146621
female infertility J:96967
impaired ovarian folliculogenesis J:96967
rib fusion J:48859
normal skeleton phenotype J:48859
small ovary J:96967
vertebral fusion J:48859
Lfngtm1Rjo/Lfngtm1Rjo
involves: 129S7/SvEvBrd * C57BL/6J 		postnatal lethality J:149312
Lfngtm1Rjo/Lfngtm1Rjo
Tg(Hes7-Lfng,-EGFP)#Ysa/0
involves: 129S7/SvEvBrd 		normal embryo phenotype J:159983
normal skeleton phenotype J:159983
Lfngtm1Seco/Lfngtm1Seco
involves: 129S6/SvEvTac * C57BL/6J 		abnormal lumbar vertebrae morphology J:131837
abnormal rostral-caudal patterning of the somites J:131837
abnormal somite development J:131837
abnormal somite size J:131837
abnormal thoracic vertebrae morphology J:131837
decreased body length J:131837
kinked tail J:131837
rib fusion J:131837
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/03/2024
MGI 6.24 		The Jackson Laboratory