Lfng Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MGI:1095413

33 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Jag2^tm1Grid/Jag2^tm1Grid Lfng^tm1Grid/Lfng⁺ involves: 129S1/Sv * C57BL/6J	decreased cochlear inner hair cell number	J:62727
Jag2^tm1Grid/Jag2^tm1Grid Lfng^tm1Grid/Lfng^tm1Grid involves: 129S1/Sv * C57BL/6J	abnormal cochlear outer hair cell morphology	J:62727
	decreased cochlear inner hair cell number	J:62727
	increased cochlear outer hair cell number	J:62727
Lfng^tm1.1Dihz/Lfng^tm1.1Dihz Tg(Lfng-LFNG)1Dihz/0 involves: 129 * C57BL/6J * CBA	normal embryo phenotype	J:184024
Lfng^tm1Grid/Lfng^tm1Grid Rfng^tm1Grid/Rfng^tm1Grid involves: 129S1/SvImJ * C57BL/6J	abnormal axial skeleton morphology	J:77247
	abnormal costovertebral joint morphology	J:48810
	abnormal vertebrae morphology	J:48810
	rib bifurcation	J:48810
	rib fusion	J:48810
	normal skeleton phenotype	J:77247
Lfng^tm1Rjo/Lfng^tm1Rjo Mesp2^{tm15.1(Lfng)Ysa}/Mesp2⁺ involves: 129S7/SvEvBrd	abnormal dorsal-ventral polarity of the somites	J:159983
	abnormal somite development	J:159983
Lfng^tm1Rjo/Lfng^tm1Rjo Mfng^tm1Cjg/Mfng^tm1Cjg B6.Cg-Lfng^tm1Rjo Mfng^tm1Cjg	abnormal embryonic hematopoiesis	J:146621
Lfng^tm1Rjo/Lfng^tm1Rjo Mfng^tm1Seco/Mfng^tm1Seco involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/NJ	abnormal rib morphology	J:149312
	abnormal skeleton morphology	J:149312
	decreased caudal vertebrae number	J:149312
	decreased survivor rate	J:149312
	postnatal lethality, incomplete penetrance	J:149312
Lfng^tm1Rjo/Lfng^tm1Rjo Mfng^tm1Seco/Mfng^tm1Seco Rfng^tm1Tfv/Rfng^tm1Tfv involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/NJ	abnormal rib morphology	J:149312
	abnormal skeleton morphology	J:149312
	decreased caudal vertebrae number	J:149312
	decreased survivor rate	J:149312
	normal limbs/digits/tail phenotype	J:149312
	postnatal lethality, incomplete penetrance	J:149312
Lfng^tm1Rjo/Lfng^tm1Rjo Ripply2^tm1.1Ysa/Ripply2^tm1.1Ysa involves: 129S7/SvEvBrd * C57BL/6 * CBA * ICR	abnormal rostral-caudal axis patterning	J:123846
	absent vertebral pedicles	J:123846
Lfng^tm1Rjo/Lfng^tm1Rjo Tg(Lfng-LFNG)1Dihz/0 involves: 129S7/SvEvBrd C57BL/6J * CBA	abnormal axial skeleton morphology	J:155378
	abnormal cervical vertebrae morphology	J:155378
	abnormal lumbar vertebrae morphology	J:155378
	abnormal thoracic vertebrae morphology	J:155378
	abnormal vertebral column morphology	J:155378
	decreased survivor rate	J:155378
	short tail	J:155378
	short vertebral column	J:155378
Lfng^tm1Rjo/Lfng^tm1Rjo Tg(Lfng-LFNG)1Dihz/Tg(Lfng-LFNG)1Dihz involves: 129S7/SvEvBrd * C57BL/6J * CBA	abnormal axial skeleton morphology	J:155378
	abnormal vertebral column morphology	J:155378
	decreased survivor rate	J:155378
	kinked tail	J:155378
	short vertebral column	J:155378
Lfng^tm1Rjo/Lfng^tm1Rjo Tg(Lfng-LFNG)2Dihz/0 involves: 129S7/SvEvBrd C57BL/6J * CBA	abnormal axial skeleton morphology	J:155378
	abnormal cervical vertebrae morphology	J:155378
	abnormal lumbar vertebrae morphology	J:155378
	abnormal thoracic vertebrae morphology	J:155378
	abnormal vertebral column morphology	J:155378
	decreased survivor rate	J:155378
	short tail	J:155378
	short vertebral column	J:155378
Lfng^tm1Rjo/Lfng^tm1Rjo Tg(Lfng-LFNG)1Dihz/0 involves: 129S7/SvEvBrd * C57BL/6J * CBA	decreased lumbar vertebrae number	J:155378
	decreased survivor rate	J:155378
	increased rib number	J:155378
	increased thoracic vertebrae number	J:155378
	male infertility	J:155378
	vertebral transformation	J:155378
Lfng^tm1Rjo/Lfng^tm1Rjo Tg(Lfng-LFNG)2Dihz/? involves: 129S7/SvEvBrd * C57BL/6J * CBA	decreased lumbar vertebrae number	J:155378
	decreased survivor rate	J:155378
	increased rib number	J:155378
	increased thoracic vertebrae number	J:155378
	male infertility	J:155378
	vertebral transformation	J:155378
Mesp2^{tm15.1(Lfng)Ysa}/Mesp2^{tm15.1(Lfng)Ysa} Not Specified	abnormal somite development	J:159983

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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