Ctsc Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ctsc
cathepsin C
MGI:109553

14 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ctsc^tm1Dgen/Ctsc^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	decreased prepulse inhibition	J:101679
	disheveled coat	J:101679
	increased thermal nociceptive threshold	J:101679
Ctsc^tm1Ley/Ctsc^tm1Ley B6.129X1-Ctsc^tm1Ley	abnormal chemokine level	J:131520
	abnormal leukocyte migration	J:131520
	abnormal response to infection	J:131520
	decreased circulating interleukin-6 level	J:131520
	impaired neutrophil recruitment	J:131520
	increased circulating interleukin-6 level	J:88160
	sepsis	J:88160
	weight loss	J:88160
Ctsc^tm1Ley/Ctsc^tm1Ley either: 129X1/SvJ-Ctsc^tm1Ley or (involves: 129X1/SvJ * C57BL/6)	abnormal cytotoxic T cell physiology	J:77312
	abnormal enzyme/coenzyme activity	J:77312
	abnormal T cell physiology	J:77312

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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