Cxcr4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cxcr4
C-X-C motif chemokine receptor 4
MGI:109563

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ccr5^tm1Kuz/Ccr5^tm1Kuz Cxcr4^tm1Qma/Cxcr4^tm1Qma involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6	abnormal nervous system physiology	J:132342
	decreased susceptibility to Retroviridae infection	J:132342
Ctnnb1^tm1Mmt/Ctnnb1⁺ Cxcr4^tm2Yzo/Cxcr4^tm2Yzo Tg(Wap-cre)11738Mam/0 Tg(Wap-Hgf)402Mig/0 FVB.Cg-Cxcr4^tm2Yzo Ctnnb1^tm1Mmt Tg(Wap-cre)11738Mam Tg(Wap-Hgf)402Mig	decreased mammary gland tumor incidence in breeding females	J:206839
Cxcr4^tm1Qma/Cxcr4^tm1Qma Gab1^tm1Wbm/Gab1^tm1Wbm involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6	abnormal intrinsic tongue muscle morphology	J:100909
	abnormal muscle precursor cell migration	J:100909
	abnormal myogenesis	J:100909
	decreased tongue size	J:100909
	hypaxial muscle hypoplasia	J:100909

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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