Pros1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pros1
protein S (alpha)
MGI:1095733

29 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pros1^tm1.1Ansc/Pros1⁺ involves: 129/Sv * C57BL/6J * FVB/N	abnormal response/metabolism to endogenous compounds	J:152423
	increased susceptibility to induced morbidity/mortality	J:152423
	increased susceptibility to induced thrombosis	J:152423
Pros1^tm1.1Ansc/Pros1^tm1.1Ansc involves: 129/Sv * C57BL/6J * FVB/N	abnormal thrombosis	J:152423
	bruising	J:152423
	decreased hepatocyte number	J:152423
	hemorrhage	J:152423
	hepatic necrosis	J:152423
	increased megakaryocyte cell number	J:152423
	intracranial hemorrhage	J:152423
	pallor	J:152423
	perinatal lethality, complete penetrance	J:152423
	thrombocytopenia	J:152423
Pros1^tm1.2Grl/Pros1⁺ involves: 129S1/SvImJ * FVB/N	abnormal blood vessel morphology	J:198769
	decreased bleeding time	J:198769
	increased vascular permeability	J:198769
	prenatal lethality, incomplete penetrance	J:198769
Pros1^tm1.2Grl/Pros1^tm1.2Grl involves: 129S1/SvImJ * FVB/N	abnormal blood coagulation	J:198769
	abnormal blood vessel morphology	J:198769
	abnormal brain vasculature morphology	J:198769
	abnormal neocortex morphology	J:198769
	abnormal thrombosis	J:198769
	abnormal vitelline vasculature morphology	J:198769
	blood vessel congestion	J:198769
	brain vascular congestion	J:198769
	enlarged brain ventricles	J:198769
	hemorrhage	J:198769
	increased vascular permeability	J:198769
	intracranial hemorrhage	J:198769
	lethality throughout fetal growth and development, complete penetrance	J:198769
	vascular smooth muscle hypoplasia	J:198769
Pros1^tm1Grl/Pros1^tm1Grl involves: 129S1/SvImJ	no abnormal phenotype detected	J:198769
Pros1^tm1Grl/Pros1^tm1Grl Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S1/SvImJ * C57BL/6 * DBA	abnormal thrombosis	J:198769
	normal cardiovascular system phenotype	J:198769
	normal mortality/aging	J:198769
Pros1^tm1Grl/Pros1^tm1Grl Tg(Tagln-cre)1Her/0 involves: 129S1/SvImJ * C57BL/6 * SJL	increased vascular permeability	J:198769
Pros1^tm1Grl/Pros1^tm1Grl Tg(Tek-cre)1Ywa/0 involves: 129S1/SvImJ * C57BL/6 * SJL	abnormal thrombosis	J:198769
	normal cardiovascular system phenotype	J:198769
	normal mortality/aging	J:198769

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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