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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Serpinb5
serine (or cysteine) peptidase inhibitor, clade B, member 5
MGI:109579
16 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Serpinb5tm1.1Pib/Serpinb5tm1.1Pib
involves: BALB/cJ * C57BL/6
no abnormal phenotype detected J:206439
Serpinb5tm1b(KOMP)Wtsi/Serpinb5tm1b(KOMP)Wtsi
C57BL/6N-Serpinb5tm1b(KOMP)Wtsi/J
abnormal sleep behavior J:211773
impaired righting response J:211773
increased circulating cholesterol level J:211773
Serpinb5tm1Zha/Serpinb5+
involves: 129
abnormal cell adhesion J:89192
decreased cell proliferation J:89192
Serpinb5tm1Zha/Serpinb5tm1Zha
involves: 129
abnormal ectoderm development J:89192
abnormal endoderm development J:89192
abnormal inner cell mass morphology J:89192
abnormal visceral endoderm morphology J:89192
absent blastocoele J:89192
absent inner cell mass proliferation J:89192
decreased cell proliferation J:89192
decreased inner cell mass proliferation J:89192
embryonic epiblast cell degeneration J:89192
embryonic lethality between implantation and somite formation, complete penetrance J:89192
failure to gastrulate J:89192

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory