Plk3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plk3
polo like kinase 3
MGI:109604

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plk3^tm1Dai/Plk3^tm1Dai involves: 129S4/SvJae * C57BL/6	abnormal tumor morphology	J:136425
	increased leiomyosarcoma incidence	J:136425
	increased liver tumor incidence	J:136425
	increased lung adenocarcinoma incidence	J:136425
	increased lung tumor incidence	J:136425
	increased tumor growth/size	J:136425
	increased tumor incidence	J:136425
Plk3^tm1Elan/Plk3^tm1Elan C57BL/6-Plk3^tm1Elan	lethality, complete penetrance	J:201467
Plk3^tm1Elan/Plk3^tm1Elan involves: 129S6/SvEvTac * C57BL/6	normal mortality/aging	J:201467
Plk3^tm1Pjs/Plk3^tm1Pjs involves: 129S6/SvEvTac * Black Swiss	abnormal cell cycle	J:175096
	abnormal cell cycle checkpoint function	J:175096
	normal neoplasm	J:175096
	polyploidy	J:175096

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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